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This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.

This study found that DKK1 and WNT10b are paracrine factors that modulate hair follicle stem cell differentiation inhibition, contributing to androgenetic alopecia by affecting Wnt signaling in androgen-sensitive dermal papilla cells after dihydrotestosterone stimulation.

This study found that dihydrotestosterone alters the balance of Wnt pathway regulators in dermal papilla cells, hindering hair follicle stem cell differentiation and contributing to hair follicle miniaturization.

This study describes a case in which a 24-year-old woman with PCOS symptoms, including irregular menstruation and excessive hair growth, showed significant improvement in androgen levels, menstrual regularity, and hair reduction after undergoing a nine-month Ayurvedic treatment plan with dietary and lifestyle modifications.

This review explores current research on how dietary phytochemicals may help manage male androgen disorders by affecting hormone levels and endocrine function, highlighting their potential therapeutic roles and mechanisms in hormonal health, but does not report specific results.

This study found that oral contraceptives, particularly those combining ethinyl estradiol with progestins like drospirenone and cyproterone acetate, are effective in treating androgen-related skin conditions such as acne, hirsutism, and androgenetic alopecia by reducing excess androgens and sebum production.

In this cross-sectional study, researchers observed that patients with hidradenitis suppurativa, particularly women, had lower 2D:4D finger length ratios compared to healthy controls, suggesting a potential link to prenatal androgen exposure and disease severity, though further prospective research is needed to confirm this hormonal impact.

This study found that methadone use in HCV-infected male veterans was associated with a significant increase in the risk of advanced liver fibrosis.

In this study, a significant negative correlation was observed between the 2D:4D digit ratio and maxillary sinus volume in men, suggesting an androgenic hormone influence on sinus volume development.

This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.

This preclinical study observed that a nanoencapsulated ingredient complex, AcPi, may prevent hair follicle aging and hair loss by reducing oxidative stress, enhancing mitochondrial activity and WNT/β-catenin signaling, and controlling androgenic metabolism when tested on human scalp cultures.

This analysis explores the potential benefits of various nutraceuticals, such as Ashwagandha, Cinnamon, and Fenugreek, in managing Polycystic Ovarian Disease, suggesting these may improve menstrual regularity, insulin sensitivity, and other symptoms when used alongside conventional treatments.

This research explores the pathogenesis of benign prostatic hyperplasia and evaluates the combined effect of finasteride and anastrozole in treating BPH in a rat model, but reports no new results yet.

This study is designed to explore the pathogenesis of BPH and assess the effectiveness of combining finasteride and anastrozole as a treatment in rats, with a focus on genetic polymorphisms and hormone regulation.

This article presents the SH-1 molecule as a novel AR antagonist for androgenetic alopecia treatment, highlighting its tissue-specific action and potential for commercialization, but provides no new clinical results.

This source describes SH‑1 as a next-generation androgen receptor antagonist designed for localized treatment of androgenetic alopecia, aiming to reverse follicular miniaturization while maintaining endocrine balance. Unlike traditional therapies, SH‑1 offers tissue-specific action, avoiding systemic effects.

This review examines the pathophysiology of PCOS and reports that myoinositol may improve menstrual regularity, insulin sensitivity, and reproductive outcomes, with comparable efficacy to metformin and often better tolerability.

This study found that SNPs in the MVK, ARPC1B, and CA2 genes may indicate a genetic predisposition for severe acne related to steroidogenesis.

This review discusses the crucial role of sex hormones in maintaining and influencing skin health, suggesting ongoing research into hormonal treatments for skin conditions due to life stage changes.

This study suggests that estrogen in contraceptive therapy may affect hair growth, potentially correcting hair loss under certain hormonal conditions; however, applying these findings to humans should be done cautiously.

In this study, treatment targeting the estrogen-androgen balance reduced hair loss in 74 out of 104 women with androgenetic alopecia, with some experiencing hair regrowth.

In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.

This case study highlights a testosterone- and cortisol-secreting adrenal oncocytic neoplasm in an 18-year-old woman, illustrating the role of surgical excision in resolving hyperandrogenism and restoring menstruation.

This study found that women with androgenic alopecia often have increased dihydrotestosterone levels, suggesting potentially enhanced activity of 5-alpha-reductase, with the saliva free testosterone level providing valuable hormonal background information.

The project aims to validate a nutritional intervention targeting the Redox–NO–Androgen Axis to restore mitochondrial, endothelial, and hormonal balance in male health disorders related to oxidative stress.

In this study, researchers found that estrogens activate and androgens inhibit brown adipose tissue thermogenesis via the VMH, affecting energy balance and suggesting targets for treating cachexia and obesity.

This article explores the Ayurvedic perspective on PCOS pathogenesis and suggests that treatments focusing on balancing tridoshas and enhancing digestion may be effective, but it reports no new clinical results.

In this case report, a 21-year-old woman with PCOS and obesity underwent bariatric surgery, leading to significant weight loss and improved hormonal balance, which alleviated her hyperandrogenism symptoms like hirsutism and irregular periods.

This literature review provides insights into the multifactorial causes of hair loss, highlighting genetic, hormonal, immune, and environmental factors, and summarizes preventive strategies like balanced nutrition and stress management to promote healthier hair.

This study found that the co-activator CBP enhances the agonistic action of hydroxyflutamide on androgen receptors, suggesting a mechanism for therapy resistance in prostate cancer.