11 citations
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January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that LY320236 is a competitive inhibitor of type I and a non-competitive inhibitor of type II steroid 5alpha-reductase, indicating its potential as a dual inhibitor with differing modes of activity.
10 citations
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June 2021 in “Primates” This study found that wild geladas in Ethiopian crop areas experienced higher levels of human disturbance and health issues, such as increased parasitic infections, compared to those in pasture areas.
10 citations
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July 2019 in “Journal of Asia-Pacific Entomology” This study suggests that ultra-fine powders of steamed and lyophilized mature silkworms may have enhanced pharmacological effects compared to fine powders, possibly due to their smaller particle size.
10 citations
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January 2019 in “Journal of Chromatography B” This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
9 citations
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July 2020 in “Journal of Dermatology” This study found that diffuse and pseudo-fringe sign patterns are common in Asian patients with frontal fibrosing alopecia, and that treatments combining antiandrogens or antimalarials with topical therapy are effective.
8 citations
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January 2020 in “Skin appendage disorders” This review found that supplements containing saw palmetto may improve hair quality and density in patients with androgenetic alopecia and telogen effluvium, but more large-scale RCTs are needed for conclusive evidence.
8 citations
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October 2015 in “Asian Journal of Chemistry” A new method was created to accurately measure minoxidil and aminexil in hair loss treatments.
8 citations
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July 2012 in “Annals of biomedical engineering” This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
8 citations
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January 2011 in “Organic and Biomolecular Chemistry” Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.
7 citations
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July 2021 in “Molecules/Molecules online/Molecules annual” This study demonstrated that an LC/MS-MS method could effectively detect and quantify the vitamin B3 vitamer nicotinamide in human hair, suggesting its potential use for long-term deficiency examination.
7 citations
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April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.
7 citations
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January 2016 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that adding simvastatin to ongoing metformin treatment reduced certain androgen levels in women with non-classic congenital adrenal hyperplasia and abnormal glucose metabolism, suggesting a potential therapeutic benefit.
7 citations
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February 2014 in “Talanta” This study developed an advanced HPLC-ESI-ion trap MS(n) method for the structural identification of cyclosporin A analogs CyA and CyC and reported the first MS(n)-aided identification of a new CyA analog.
6 citations
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May 2021 in “Stem Cell Reviews and Reports” This study identified and characterized progenitor cells from equine feet that may play a role in the pathogenesis and recovery of laminitis, suggesting potential therapeutic targets for treatment.
5 citations
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July 2017 in “Women & Health” This study found that nursing women in the West Bank of Palestine who lived in cities and consumed energy beverages had higher blood zinc levels.
5 citations
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June 2011 in “PLoS ONE” This study found that biologic rhythms in mammoth hairs differed from those in modern human hair, with variations in growth rates and mineral content providing insights into the lifestyle and behavior of extinct species.
4 citations
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December 2018 in “Macedonian Journal of Chemistry and Chemical Engineering” This study developed a reliable RP-HPLC-DAD method, finding that amino acid concentrations in bleached hair decrease with higher hydrogen peroxide levels, notably affecting cystine.
4 citations
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January 2018 in “Forensic Science International” This study reported that a newly developed UHPLC-MS/MS method detected illegal synthetic hair-growth compounds in 10% of 76 hair-growth products, highlighting the need for ongoing monitoring to protect public health.
3 citations
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June 2021 in “Journal of affective disorders” This study suggests that hair cortisol and cortisone may moderate the relationship between work stress and depressive symptoms in Chinese fishermen, although their mechanisms differ.
3 citations
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January 2017 in “Journal of Pakistan Association of Dermatology” This study found a significant association between low serum ferritin levels and nonscarring alopecia in women, suggesting the importance of addressing iron deficiency for treatment effectiveness.
3 citations
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October 2014 in “Pharmaceutical Development and Technology” This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.
3 citations
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October 1994 in “Journal of Labelled Compounds and Radiopharmaceuticals” This synthesis report details the successful development of a C-14 labeled isotopomer of LY300502, a 5α-reductase inhibitor, through a multi-step radiochemical process.
2 citations
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December 2021 in “Scientific reports” In this study, scalp hair sweating was a significant predictor of hair cortisol levels in healthy adults, while BMI and perceived stress, although associated, did not significantly predict cortisol levels.
2 citations
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March 2021 in “Journal of Cosmetic Dermatology” This study found that human umbilical cord-derived mesenchymal stromal cell-conditioned media was safe and positively affected hair regeneration in 86.6% of participants in a pilot study.
2 citations
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November 2019 in “Cancer reports” This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.
2 citations
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January 2013 in “Elsevier eBooks” This chapter reviews the causes and underlying steroid pathways of hirsutism and virilization in women, detailing relevant conditions and laboratory assays without reporting new clinical results.
1 citations
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October 2023 in “Life science alliance” This study observed that pantethine, a vitamin B5 precursor, attenuates tumor growth in immunocompetent mice by enhancing antitumor immunity, but its effect is limited by immune cell exhaustion over time.
1 citations
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April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study is the first to document alopecia in Guadalupe fur seals in the Northeast Pacific Ocean, finding that it may result from nutritional stress due to higher sea surface temperatures.
1 citations
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January 2021 in “Open Access Journal of Cancer & Oncology” In this study, the Trivedi Effect®-Consciousness Energy Healing Treatment was reported to significantly increase the solubility and isotopic abundance ratios of flutamide, potentially improving its stability and efficacy.
1 citations
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November 2019 in “International Journal of Women's Dermatology” Ketoconazole shampoo can cause rare pink hair discoloration.