179 citations,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
53 citations,
January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Reduced AR gene methylation may cause early pubic hair growth in girls.
47 citations,
November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
January 2014 in “Cosmoderma” The document concludes that personalized treatment plans for hair loss in Asian men are necessary and more research is needed to develop effective guidelines.
5 citations,
September 2023 in “Journal of ethnopharmacology” Purslane has many health benefits and potential uses in medicine, food, and farming.
86 citations,
October 2013 in “Dermatologic Clinics” Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.
17 citations,
June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
3 citations,
October 2022 in “PloS one” Scientists have developed a method to keep chicken feather follicles alive and structurally intact in a lab for up to a week.
10 citations,
March 2019 in “Human Genetics” A genetic mutation in the SGK3 gene causes hairlessness in Scottish Deerhounds and may relate to human hair loss.
189 citations,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
90 citations,
May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
16 citations,
February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
32 citations,
March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
45 citations,
August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
36 citations,
August 2018 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.
July 2022 in “Research Square (Research Square)” Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.
6 citations,
May 1997 in “Journal of Dermatological Science” Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
21 citations,
May 2017 in “International Journal of Dermatology” Overweight smokers have worse hair loss.
January 2015 in “Springer eBooks” Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
47 citations,
December 2006 in “Therapy” The dietary supplement helped increase hair growth in women with hair loss.
13 citations,
January 2016 in “Journal of Ophthalmology” A new eyelid shampoo improved eyelid hygiene and eyelash length in people with Meibomian Gland Dysfunction.
23 citations,
July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
40 citations,
November 2009 in “Experimental Dermatology” The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
233 citations,
November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
22 citations,
November 2008 in “International Journal of Dermatology” A mix of 5-aminolevulinic acid and iron ion can speed up hair growth.
25 citations,
January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
27 citations,
January 2015 in “International Journal of Trichology” The supplement helps improve hair growth and reduce hair shedding.
There are many treatments for common hair loss, but more trials are needed to decide which are best.