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Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

EDA2R gene linked to hair loss.