4 citations
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February 2025 in “Molecular Medicine” In this study, ALA-PDT significantly reduced lipogenesis in an acne-like model by upregulating OLR1 and suppressing lipid accumulation, highlighting a potential therapeutic target.
4 citations
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December 2014 in “European Journal of Chemistry” This study synthesized and characterized new 2-hydroxypyrrolidine/piperidine derivatives using FeCl₃·6H₂O as a catalyst, but it reports no biological or clinical results.
3 citations
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July 2019 in “Journal of Cosmetic Dermatology” This study found that a shampoo with a selective TAAR agonist reduced hair shedding during brushing by 31% in women and contracted the arrector pili muscle.
2 citations
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July 2019 in “PLOS ONE” This study found that the CYP3A4 rs4646437 genotype was significantly associated with ALT elevation in Japanese patients undergoing asunaprevir plus daclatasvir therapy for chronic HCV infection, suggesting genotyping may help in monitoring patients safely.
2 citations
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August 2021 in “Photodiagnosis and Photodynamic Therapy” In this study, 5-aminolevulinic acid photodynamic therapy did not improve hair growth in patients with androgenetic alopecia but was safe and slightly reduced scalp sebum secretion.
1 citations
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September 2025 in “Journal of Zhejiang University SCIENCE B” This abstract outlines the current understanding of cutaneous squamous cell carcinoma (cSCC), identifying it as the second most common non-melanoma skin cancer with risk factors like UV exposure and immunosuppression. It highlights cSCC's potential to metastasize and become fatal, affecting 2%-5% of in situ cases.
1 citations
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September 2023 in “Rheumatology advances in practice” This case report describes a 42-year-old woman with rheumatoid arthritis who developed extensive impetiginized pityriasis amiantacea potentially linked to her anti-TNF-α therapy with golimumab. Discontinuing the drug and other treatments led to significant clinical improvement within a month.
1 citations
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January 2023 in “Life sciences” This study demonstrated that elevated GABA levels can worsen stress-induced hair growth inhibition in mice, while GABAA antagonists like ginkgolide A may help alleviate these effects.
1 citations
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April 2022 in “JAAD case reports” In this case report, researchers observed that a 47-year-old woman developed pityriasis amiantacea after using topical minoxidil, suggesting a potential new etiology for this scalp condition.
1 citations
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June 2020 in “Dermatologic Therapy” COVID-19 can cause various skin issues, including rashes and 'COVID toes', and may worsen autoimmune diseases or affect men with baldness more severely.
1 citations
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January 2019 in “PubMed” The authors describe a case of pityriasis amiantacea in a woman following bone marrow transplantation, potentially linked to melphalan conditioning, which responded to treatment with mineral oil and specific shampoos.
March 2026 in “FEBS Open Bio” This study found that 5-aminolevulinic acid combined with ferric ammonium citrate stimulated hair follicle growth and induced hair-like structures in human hair follicle models, suggesting its potential as a treatment for hair loss.
January 2026 in “Journal of Cosmetic Dermatology” In this 10-patient exploratory study, the researchers found that topical application of 4-aminopyridine 5% combined with microneedling did not improve hair density or quality in men with androgenetic alopecia, suggesting limited efficacy in this context despite promising results in animal wound models.
August 2025 in “Frontiers in Nutrition” This study found that serum amino acid profiles changed significantly following laparoscopic sleeve gastrectomy in patients with obesity, and identified serum leucine levels as an independent risk factor for postoperative alopecia.
The researchers reported that a 4-aminopyridine-loaded gel promoted wound healing and hair follicle regeneration in burn models, suggesting it might be a promising alternative to existing burn treatments.
November 2023 in “Skin Appendage Disorders” This case report describes a rare instance of pityriasis amiantacea and cutis verticis gyrata occurring in a 32-year-old man with B-cell acute lymphoblastic leukemia, highlighting this previously unreported dermatological manifestation and stressing the importance of clinical awareness.
July 2022 in “Biomedicines” This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.
March 2022 in “Research Square (Research Square)” This study found that 4-aminopyridine significantly improved skin wound healing by enhancing wound closure, tissue regeneration, and cellular interactions involved in repair processes.
November 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that 4-aminopyridine, a potassium channel blocker, greatly improves skin wound healing by accelerating wound closure, enhancing tissue regeneration, and promoting hair follicle neogenesis.
November 2021 in “Research Square (Research Square)” This study found that 4-aminopyridine significantly improves skin wound healing by enhancing various cellular and molecular processes, suggesting its potential for rapid translational development in wound treatment.
April 2021 in “Animal Bioscience” This study found that 5-aminolevulinic acid significantly improved chicken sperm motility and increased mitochondrial membrane depolarization, while decreasing ATP levels.
April 2021 in “Research Square (Research Square)” This study found that the new cocrystal formulation KET-PABA improved the antimycotic efficiency of ketoconazole and induced an anti-inflammatory response without causing skin sensitization in mice.
October 2020 in “The American journal of gastroenterology” This case study reports a previously undescribed cause of drug-induced autoimmune hepatitis triggered by para-aminobenzoic acid (PABA), emphasizing the need for caution with this supplement.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.
December 2004 in “Microbial Ecology in Health and Disease” This study found that Pityriasis amiantacea was associated with Staphylococcus aureus infection, especially in young women of Bedouin origin, and responded well to antibiotic and topical treatments.
March 1983 in “Annals of Internal Medicine” This letter to the editor mentions reports of hair loss potentially related to 5-aminosalicylic acid enemas, but suggests it may be due to telogen effluvium from severe inflammatory bowel disease rather than a direct effect.
238 citations
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May 1989 in “Journal of Investigative Dermatology”
27 citations
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May 2010 in “Dermatologic surgery” This study found that photodynamic therapy with methyl 5-aminolevulinic acid was ineffective for treating alopecia totalis, even with microneedle rolling to enhance drug delivery.
15 citations
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January 1981 in “Neonatology” This study observed that changes in amino acid levels in milk correlate with developmental events in pouch young marsupials, notably around hair follicle development and homeothermy onset.
12 citations
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August 1984 in “Genetics Research” In this study, researchers found that the naked (N) gene in mice indirectly affects the synthesis of structural proteins in mouse hair, resulting in reduced high tyrosine protein content and unusual amino acid compositions.