Cloning and Expression of Cellular Retinoic Acid Binding Protein I Gene in Inner Mongolian Cashmere Goats

    January 2012
    Hua Li
    TLDR The CRABP I gene in cashmere goats is highly conserved but has unique features at specific amino sites.
    The study successfully cloned the cDNA sequence of the CRABP I gene in Inner Mongolian cashmere goats and analyzed its protein structure and expression. The CRABP I gene's open reading frame (ORF) was 414 bp and showed high similarity with other species. The protein lacked signal peptides, transmembrane segments, and glycosylation sites, and its secondary structure mainly consisted of β sheets, α helixes, and loops. The gene was most highly expressed at 90 days of embryo development compared to 100, 120, and 130 days. The study concluded that while the ORF of the CRABP I gene is conserved across species, specific characteristics at amino sites 33 and 123 are unique to cashmere goats. Further research is needed to understand the gene's polymorphism and its regulatory mechanisms in hair follicle sebaceous glands.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 348 results

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 3 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

    Similar Research

    5 / 239 results