August 2025 in “Chronobiology International” In this study, college students with an evening chronotype were found to be at greater risk for androgenetic alopecia, potentially due to altered circadian rhythms as indicated by shifts in heart rate patterns and clock gene expression in hair follicles.
In this study, researchers found a strong association between premature graying of hair and deficiencies in vitamin D and B12, hypothyroidism, and deranged iron profiles, along with higher stress, altered appetite, smoking, and sleep pattern issues, significantly impacting quality of life.
This study found a significant association between premature greying of hair and deficiencies in vitamin D, vitamin B12, hypothyroidism, and disrupted iron profiles, alongside lifestyle factors like stress and smoking.
32 citations
,
September 2010 in “Stress” This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.
5 citations
,
May 1983 in “Australian journal of biological sciences” This study found that concurrent administration of cycloleucine with ethionine prevented the weakening of wool fibers in sheep, whereas reduced glutathione did not have the same effect.
48 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews the genetic and protein interactions involved in hair growth, highlighting regulatory sequences, expression patterns, and potential genetic modifications, but presents no new experimental findings.
8 citations
,
July 2019 in “Endocrine connections” This study found that post-finasteride syndrome patients showed a tissue-specific methylation pattern of the SRD5A2 promoter in cerebrospinal fluid, potentially affecting neuroactive steroid levels and related behavioral symptoms.
5 citations
,
August 2018 in “International Journal of Dermatology” This study suggests obstructive sleep apnea may increase the risk of male-pattern baldness in men with a family history of hair loss, and links low serum transferrin saturation levels to both conditions.
61 citations
,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.
17 citations
,
October 2017 in “Scientific reports” This study found that Super Merino sheep have a higher wool follicle density, finer fleece, and distinct gene expression compared to Small Tail Han sheep, which may inform future breeding and genetic interventions.
3 citations
,
July 2019 in “Experimental Dermatology” This study reported that polyamine levels, especially N-acetyl polyamines, were higher in the vertex region of the scalp than in the occipital region in patients with male and female pattern hair loss.
1 citations
,
September 2023 in “Genes” This study found no significant difference in CUX1 core promoter methylation levels between different lambskin patterns in Hu sheep, suggesting other mechanisms influence CUX1 expression related to hair follicle development.
February 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study aims to assess how daily life factors affect sleep patterns and describe individual sleep changes across the year, with results to be published in future research.
103 citations
,
March 2011 in “PLoS Biology” This study found that a mutation in the BMP12/GDF7 gene is associated with the Naked neck trait in chickens, reducing neck feathering due to altered signaling pathways.
17 citations
,
June 2020 in “Animals” This study identified differentially expressed mRNAs and lncRNAs in Hu sheep hair follicles, suggesting certain genes and pathways are involved in the development of wool curvature patterns.
June 2021 in “Research Square (Research Square)” This study reports that melatonin influences gene expression related to cashmere growth cycles in Inner Mongolian cashmere goats, potentially aiding in understanding and enhancing cashmere yield through molecular regulation.
July 2023 in “Frontiers in veterinary science” In this study, researchers analyzed skin samples from Dorper sheep to identify 395 differentially expressed long non-coding RNAs (lncRNAs) linked to hair follicle growth phases, suggesting these lncRNAs may play a role in the regulation of hair shedding through pathways like estrogen and PI3K-Akt signaling.
6 citations
,
May 2020 in “Scientific reports” In this study, microarray and proteomic analyses indicated that genes involved in immune response, receptor binding, and growth factor activity might influence wool fibre diameter in sheep.
July 2023 in “Journal of ayurveda and integrated medical sciences” This case report details the treatment of a 28-year-old woman with PCOS symptoms, including irregular menstruation, weight gain, and hair loss, using Ayurvedic management after ultrasound showed a bilateral PCO pattern.
10 citations
,
January 2009 in “Elsevier eBooks” This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.
May 2013 in “Springer eBooks” Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
14 citations
,
June 2022 in “BMC genomics” This study identified key genes involved in hair follicle development in Merino sheep, offering insights for improving wool production and providing a basis for future breeding programs.
6 citations
,
February 2023 in “Genes” This study found that overexpression of the CUX1 protein promotes proliferation of Hu sheep dermal papilla cells and affects key genes in the Wnt/β-catenin signaling pathway.
1 citations
,
December 2021 in “Androgens” This review discusses the effects of neuroactive testosterone metabolites on CNS functions and suggests their potential as therapeutic options for neurological disorders, but reports no new clinical results.
2 citations
,
February 2021 in “Journal of comparative pathology” In this study, hyperplastic layers of scabietic sheep skin showed expansive keratin labeling, indicating altered keratin expression compared to healthy skin.
January 2024 in “Diabetes & metabolism journal” This review explored how the circadian system might influence diabetes development and management, highlighting mismatches like disrupted sleep-wake cycles and gene mutations that could worsen diabetes, and suggests targeting these for future diabetes prevention and treatment strategies.
In a controlled study, researchers observed that lambs exposed to colder temperatures had increased wool growth, thicker skin, altered physiological traits, and activated specific molecular pathways, highlighting potential targets for enhancing cold tolerance, welfare, and productivity in sheep breeds.
July 1996 in “Annals of Internal Medicine” This correspondence reported significant variability between quantitative PCR and bDNA assays for measuring Hepatitis C virus RNA in high-titer specimens, challenging the reliability of the Chiron assay.
3 citations
,
December 2021 in “Proteins” This study found that straight crimp mutant wool differs from crimpy wool in the layout of cortical cells and the relative proportions of keratin and keratin-associated proteins.
9 citations
,
April 2018 in “Biology of reproduction” This study concluded that dietary changes alter serum progesterone and estradiol levels in late gestation ewes, likely due to metabolism rather than changes in placental steroid synthesis.