Transcriptomic Analysis of Skin Tissue Reveals Molecular Mechanisms of Thermal Adaptation in Cold-Exposed Lambs

    May 2025 in “ Animals
    Mengyu Feng, Kaixi Ji, Yutao Li … Guo Yang
    Studysummary In a controlled study, researchers observed that lambs exposed to colder temperatures had increased wool growth, thicker skin, altered physiological traits, and activated specific molecular pathways, highlighting potential targets for enhancing cold tolerance, welfare, and productivity in sheep breeds.
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    Research cited in this study 8

    1. The Effect of EGR1 on the Proliferation of Dermal Papilla Cells Genes · 2022
    2. Skin Transcriptome Analysis Identifies Key Genes Underlying Fur Development in Chinese Tan Sheep During Birth and Er-Mao Periods Gene · 2022
    3. Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep BMC Biology · 2021
    4. Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China Molecular Biology and Evolution · 2020
    5. Skin Transcriptome Profiling of Changthangi Goats Highlights the Relevance of Genes Involved in Pashmina Production Scientific reports · 2020
    6. JunB Defines Functional And Structural Integrity Of The Epidermal-Pilosebaceous Unit In The Skin Nature Communications · 2018
    7. Identification of Genes and Proteins Associated with Anagen Wool Growth Animal genetics · 2016
    8. Identification of Skin-Expressed Genes Possibly Associated with Wool Growth Regulation of Aohan Fine Wool Sheep BMC Genetics · 2014