research Change In Hair Color In Mice Induced By Injection Of Alpha-MSH
Injecting α-MSH made mice's hair turn black.
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180-210 / 1000+ resultsresearch Isolation of Intermediate Filament Assemblies from Human Hair Follicles
Researchers isolated and identified structural components of human hair follicles, providing a model for studying hair formation.
research Minoxidil Use in Androgenic Alopecia
Minoxidil helps stimulate hair growth and enlarge small follicles in common hair loss, but doesn't stop it, and its effects can be boosted when combined with finasteride.
research Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus: More Than a Coincidence
The conclusion is that having both Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus may suggest a shared immune response in certain people, and a mix of antimalarial drugs and 5-alfa-reductase inhibitors is recommended for treatment.
research RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells
RE-ORGA, a Korean herb extract, may help prevent hair loss.
research Medicinal Plants Used in Mexico for the Treatment of Alopecia
Mexican medicinal plants are used to treat hair loss.
research Recommendations on the Clinical Management of Androgenetic Alopecia: A Consensus Document from the Spanish Group of Trichology of the Spanish Academy of Dermatology and Venereology
Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.
research Effects of Solvent System and Storage Condition on Chemical Stability of 5α-Reductase Inhibitor Compounds in Tectona Grandis Leaf Extracts
Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
research Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition
Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
research Granulomatous Scarring Alopecia Associated With Rheumatoid Arthritis: A Case Report
A woman with rheumatoid arthritis had a unique type of scarring hair loss not caused by infection, requiring early treatment to avoid permanent hair loss.
research Male-Pattern Baldness, Common Latent Viruses, and Microcompetition
Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.
research Crystal Structure of Steroid Reductase SRD5A Reveals Conserved Steroid Reduction Mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research The Effects of Oral 5-Alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in a Rat Model
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research Activity of Steroid 4 and Derivatives 4a–4f as Inhibitors of the Enzyme 5α-Reductase Type 1
Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
research Plasmacytoid Dendritic Cells as a Key Player in the Initiation Phase of Alopecia Areata-Induced C3H/HeJ Mouse
Plasmacytoid dendritic cells, which overproduce IFN-α, may play a crucial role in starting alopecia areata, an autoimmune disease causing hair loss.
research Androgenetic Alopecia Treated With Topical Minoxidil: A Case Report and Review of Treatment Options
Topical minoxidil improved hair loss in a patient when used consistently.
research Risk of Rhabdomyolysis from 5-Alpha Reductase Inhibitors
Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.
research Inhibitors of 5α-Reductase-Related Side Effects in Patients Seeking Medical Care for Sexual Dysfunction
5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
research 5-Alpha-Reductase Inhibitor Treatment for Frontal Fibrosing Alopecia: An Evidence-Based Treatment Update
5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.
research Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction and metabolism.
research Receipt of 5-Alpha Reductase Inhibitors Before Radical Cystectomy: Do They Render High-Grade Bladder Tumors Less Aggressive?
Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.
research Exercise Activates the PI3K-AKT Signal Pathway by Decreasing the Expression of 5α-Reductase Type 1 in PCOS Rats
Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
research Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands
New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.
research Association of Suicidality and Depression with 5α-Reductase Inhibitors
5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.
research Design, Synthesis, and Biological Evaluation of Novel Androst-3,5-Diene-3-Carboxylic Acid Derivatives as Inhibitors of 5α-Reductase Type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research The Risk of Dementia with the Use of 5 Alpha Reductase Inhibitors
Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.
research The Pregnant Urologist: Occupational Risks and Safety Measures
Pregnant female urologists should avoid certain drugs and use protective measures to stay safe.
research The Connection of 5-Alpha Reductase Inhibitors to the Development of Depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.