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This study supports that an antibody response against anagen-specific hair follicle antigens, including trichohyalin and keratin 16, may play a role in alopecia areata.

In this study, mixing mouse epithelial and dermal cells was the most successful method for reconstituting hair follicles in mice, with the hair patch assay providing the quickest results.

This study observed that techniques using autologous cellular micrografts to isolate hair follicle stem cells from scalp biopsies show promise in improving hair density and thickness for androgenetic alopecia, offering a minimally invasive and potentially more compliant alternative to existing treatments like finasteride and minoxidil.

This study found that expressions of TLR-3, TLR-7, TLR-8, and TLR-9 were significantly higher in alopecia areata patients compared to healthy controls, indicating a potential role in disease autoimmunity.

This study found that hair growth was maintained in alopecic sites using scalp autografts with triamcinolone acetonide, but homografts were typically rejected.

This study found that prophylactically administering amotosalen-treated allogeneic donor T cells at transplantation significantly improved immune reconstitution and protection against murine cytomegalovirus infection without inducing graft-versus-host disease.

This study found that prevascularizing dermal matrices with adipose tissue-derived microvascular fragments improved vascularization and allowed earlier successful skin grafting in a bradythrophic wound model.

In this study, only a subset of proposed biomarkers universally responded to priming in mesenchymal stromal cells, suggesting limited utility for standardized potency assays across different MSC types and conditions.

This study introduces a new multiaxial bioreactor system that uniformly stretches tissue-engineered skin grafts and improves skin tissue maturation through enhanced cellular distribution and environmental monitoring.

This study suggests that novel diagnostic, preventive, and treatment approaches for autoimmune diseases like alopecia areata may be developed by identifying hub genes, and highlights the usefulness of machine learning and bioinformatics in finding new disease biomarkers.

This study found that follicular unit-like wigs made from a polycaprolactone matrix exhibited good histocompatibility in New Zealand white rabbits, with reduced inflammatory cell infiltration compared to a polypropylene matrix.

This study found that adding Triamcinolone to the local anesthetic solution and administering PRP sessions significantly improved hair transplantation outcomes, with gene expression indicating SRD5A2's role in transplant success.

This study found that the presence of CD3(+) T-cells within empty follicular fibrous tracts is a reliable indicator for diagnosing diffuse alopecia areata instead of pattern hair loss.

Machine learning can use blood tests to help predict moderate-to-severe alopecia areata.

In this study, single-cell sequencing revealed clonal expansions of CD4+ and CD8+ T cells in murine and human alopecia areata, supporting the development of predictive models for human disease.

This study found that both Th1 and Th2 immune responses, along with IL-23 and IL-32 cytokine pathways, are active in alopecia areata lesions, and corticosteroid injections significantly altered these immune markers.

This study focused on developing and validating standardized methods to reliably assess hair growth and scalp health in androgenetic alopecia, finding significant differences in hair parameters such as vellus and terminal hair counts, density, and thickness between affected and standardized areas.

This study concluded that estimating split thickness skin graft take by observation is as reliable as using the Image J digital program.

This study reports that the metanephrine content was significantly higher in patients with alopecia areata compared to those without the condition.

This study found that transverse sections of scalp biopsies showing lower anagen:non-anagen hair ratios and presence of pigment casts help differentiate alopecia areata from androgenetic alopecia.

This study found that intradermal injections of cultured autologous dermal sheath cup cells for androgenetic alopecia showed hair loss stabilization at 24 months without serious adverse effects and a sustained response in some participants.

This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.

In this study, activated PRP injections appeared to promote hair growth in AGA-affected scalp skin transplanted onto mice, compared to non-activated PRP.

Permanent hair loss after a stem cell transplant can be a sign of chronic immune system attack on the scalp.

This study found that patients with alopecia areata had altered levels of inflammatory and coagulation markers, suggesting an association with disease pathogenesis and potential predictive value.

This study reported that among five children and adolescents who developed new-onset atopic dermatitis after allogeneic hematopoietic stem cell transplantation, topical therapy and skin care improved their skin condition and atopic dermatitis severity scores, potentially reducing the need for excessive immunosuppressive therapy.

This study reported that using autologous micro-grafts according to the Rigenera® protocol may improve hair restoration and increase hair follicle numbers in patients with androgenetic alopecia after 6 to 9 months.

This article discusses the importance of preparing and storing human hair follicle grafts during micrograft transplantation in hair restoration surgery and reports no new research findings.

This study found that transverse sections of scalp biopsies, particularly looking at the anagen:non-anagen hair ratio and presence of pigment casts, effectively distinguish alopecia areata from androgenetic alopecia.

This study established an IRGDS model with diagnostic capability for alopecia areata, which may serve as an auxiliary marker for the condition.