November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Imaging Mass Cytometry effectively visualizes multiple biomarkers in alopecia areata, enhancing analysis of immune cell and tissue interactions in hair pathology.
December 2023 in “Frontiers in Medicine” In this study, the researchers found that measuring tacrolimus levels in scalp hair could be a reliable method for monitoring drug exposure in kidney transplant recipients, offering an alternative to frequent blood tests by utilizing self-collected hair samples.
17 citations
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November 2017 in “PLoS ONE” This study observed dynamic behaviors such as cluster formation, migration, and active proliferation of transplanted bone marrow cells in a mouse model, providing insight into cellular-level changes post-transplantation.
July 2024 in “Journal of Investigative Dermatology” This study found that in mice with alopecia areata, CD8+ T cells showed clonal expansion and specific regulatory networks, which might help identify new therapeutic targets for patients not responding to JAK inhibitors.
11 citations
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June 1999 in “Seminars in Cutaneous Medicine and Surgery” This article compares modern hair restoration techniques for androgenic alopecia, focusing on procedure times, labor, and costs, but it does not provide new clinical findings.
1 citations
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February 2015 in “Clinical and Experimental Dermatology” This case report details a patient who developed multiple skin cancers within one year of receiving an allogeneic haematopoietic cell transplant for chronic lymphocytic leukaemia.
8 citations
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April 2023 in “Dermatology Practical & Conceptual” This study reported that higher monocyte lymphocyte ratio, monocyte high-density lipoprotein cholesterol ratio, and platelet lymphocyte ratio were associated with increased risk of developing alopecia areata, suggesting their potential as diagnostic markers.
15 citations
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June 2020 in “Journal of Orthopaedic Translation” This study introduced and validated a reliable and reproducible metal-free mouse model for ACLR surgery, providing a new tool to investigate the molecular mechanisms of graft-tunnel healing.
3 citations
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May 2018 in “Journal of Cosmetic Dermatology” This study reported that the most reliable way to differentiate alopecia areata from androgenic alopecia is by detecting intrafollicular CD3 and CD8 cell density, with CD3 being the most specific and sensitive marker.
January 2018 in “Journal of The American Academy of Dermatology” This study reports various methods used by hair transplant surgeons to count and manage follicular grafts during follicular unit extraction hair restoration, including manual counting and the use of automated or digitalized graft counters.
June 2025 in “British Journal of Dermatology” In this retrospective study, researchers found that the diagnostic yield for alopecia skin biopsies was lower with longer durations of disease onset and suggested improving diagnostic accuracy through standardized request forms and digital pathology integration.
19 citations
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January 2007 in “Journal of medical investigation” This study found that transplanting GFP transgenic tail skin onto wild-type mice leads to partial replacement of dermis, nerves, and blood vessels by recipient tissue after six months, while epidermis, hair follicles, and sebaceous glands persist from the graft.
August 2018 in “Analysis of the application of various variants of bone plasty in victims with intraarticular fractures (Transplantology)” In this study, follicular microautotransplantation was found to be an effective outpatient surgical treatment for scarring alopecia, with transplanted follicles showing an average engraftment rate of 93.8% and providing a good cosmetic outcome that improves patients' quality of life.
3 citations
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November 2021 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a single application of autologous cellular micrografts showed short-term favorable responses in up to two-thirds of patients with androgenetic alopecia.
9 citations
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March 2017 in “Journal of Visualized Experiments” This study introduced a novel in vitro murine assay using transgenic mice to identify immunomodulatory compounds, which identified 160 potential hits from 4,398 compounds screened.
4 citations
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July 2008 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that alopecia areata patients who responded poorly to topical immunotherapy had impaired peripheral blood mononuclear cell responses to T-cell stimulants.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Abatacept may help some people with alopecia areata regrow hair.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study investigates whether lymphocytes from mice with secondary alopecia areata can effectively induce the disease in a C3H/HeH mouse model, similar to lymphocytes from mice with spontaneous disease.
11 citations
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December 2010 in “American journal of transplantation” This study describes three female islet transplant recipients who unexpectedly developed alopecia areata about 7 years post-transplant, with a possible link to immunosuppressive treatment regimens.
This study found that using micrografts and minigrafts with slits for male pattern hair loss led to satisfactory appearance outcomes, though patients experienced low hair density.
December 2023 in “Minia Journal of Medical Research” In this study, researchers found that transverse sections of alopecia areata lesions showed significantly more terminal hair follicles with perifollicular lymphocytic infiltrate compared to longitudinal sections, and this immune infiltration positively correlated with the positive hair pull test in patients.
April 2023 in “Journal of Investigative Dermatology” This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.
5 citations
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September 2017 in “PubMed” This study found that hypothermically stored amniotic membrane grafts promoted greater tissue regeneration, including basket-weave collagen matrix and follicle formation, compared to dehydrated amnion/chorion meshed grafts in a rat wound model.
November 2025 in “Journal of Investigative Dermatology” 2 citations
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May 2025 in “Diagnostics” This study found that ATR-FTIR spectroscopy combined with machine learning effectively differentiated alopecia areata patients from healthy controls with an AUC of 0.85, and also showed promise in predicting treatment response, particularly through alterations in the Amide I band.
5 citations
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March 2016 in “Experimental and molecular pathology” In mouse models of alopecia areata, this study found increased dilation of lymphatic vessels in affected mice, with associated changes in gene expression related to vascular growth and immune cell movement.
January 2019 in “Springer eBooks” Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.
January 1999 in “Chinses Journal of Hand Surgery” This study found that human hair keratin artificial tendons have low antigenity and may serve as an effective substitute for tendon repair in the upper extremities.
December 2024 in “Journal of Clinical Medicine” This study found that wound bed perfusion strongly predicts skin graft viability by correlating with lower necrosis extension on both the scalp and lower limb, unlike perfusion of the wound margin and donor skin, which showed no significant correlation.
March 2026 in “Journal of Investigative Dermatology” This study found that GPT-4o demonstrated high concordance with in-person and image-based provider assessments in generating SALT scores for alopecia areata, suggesting its potential as an adjunct tool in clinical practice for automating these assessments.