The Effects of Micro-Grafts in the Treatment of Androgenetic Alopecia

    Giancarlo Ceccarelli, Laura Robin Benedetti, Fl Ronzoni, Maurilio Sampaolesi, Laura Trovato, Alberto Graziano, Maria Gabriella Cusella De Angelis
    Studysummary This study reported that using autologous micro-grafts according to the Rigenera® protocol may improve hair restoration and increase hair follicle numbers in patients with androgenetic alopecia after 6 to 9 months. Our plain-language summary of this paper — not a Tressless recommendation.
    The study explored the use of autologous micro-grafts, specifically the Rigenera® protocol, as a treatment for androgenetic alopecia (AGA), a condition affecting 60-70% of adults worldwide. The Rigenera® protocol, previously effective in wound care and tissue regeneration, was tested on three patients to assess its long-term efficacy in promoting hair growth. Histological evaluations conducted 6 and 9 months post-application showed an increase in hair follicles, beginning of cuticle formation, and proliferation of dermal papilla. By 9 months, there was a well-organized derma with structured collagen fibers and hair follicles in the Anagen IV/Mesanagen phase. The study concluded that micro-grafts improved hair restoration, with positive subjective assessments from patients.
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