research Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene
Hairless protein affects hair follicle structure by regulating the Dlx3 gene.
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research Injectable Silk Nanofiber Hydrogels as Stem Cell Carriers to Accelerate Wound Healing
Silk nanofiber hydrogels help stem cells heal wounds faster and improve skin regeneration.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Small Molecule Agents Against Alopecia: Potential Targets And Related Pathways
New small molecule drugs could help treat hair loss.
research Sdr16c5 and Sdr16c6 Control a Dormant Pathway at a Bifurcation Point Between Meibogenesis and Sebogenesis
Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.
research The Use of Synthetic Polypeptides in Cosmetics
Synthetic polypeptides in cosmetics may help with anti-aging, but their effectiveness on real skin is uncertain.
research Adsorption of Diclofenac and PFBS on a Hair Keratin Dimer
Human hair keratin might be good for filtering out harmful substances from water.
research A Review on Hair Loss and Damage
The article concludes that understanding the causes of hair loss and using continuous treatments like minoxidil and finasteride can help manage it, despite potential side effects.
research Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact
Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Influence of Oxidative and Reductive Treatment on Human Hair: Analysis of Hair Damage
Chemical treatments and daily stresses damage hair, especially the cuticle layer.
research The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth
Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial
Spironolactone most effective for hirsutism, but has side effects.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
research Urinary Steroids in Women with Androgenic Alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research Neural Stem Cells Restore Hair Growth Through Activation of the Hair Follicle Niche
Neural stem cell extract can safely promote hair growth in mice.
research Defining Metabolic Flexibility in Hair Follicle Stem Cell Induced Squamous Cell Carcinoma
Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia
Using minoxidil on the scalp can help grow hair for people with hereditary baldness.
research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque
Finasteride and minoxidil together promote hair growth better than either alone.
research Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica
Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.
research A New Spectrophotometric Method for the Determination of Finasteride in Tablets
New method accurately measures finasteride in tablets.
research Rapid Determination of Minoxidil in Human Plasma Using Ion-Pair HPLC
Quick method to measure minoxidil in blood, accurate and useful for labs.
research Electrochemical Determination of Minoxidil in Different Pharmaceutical Formulations by Flow Injection Analysis
Method accurately measures minoxidil concentration in medicines.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research Topical Minoxidil Reduces Blood Pressure
Minoxidil can lower blood pressure in some people.
research Simultaneous Determination of Quercitrin, Afzelin, Amentoflavone, Hinokiflavone in Rat Plasma by UFLC-MS-MS and Its Application to the Pharmacokinetics of Platycladus Orientalis Leaves Extract
Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.
research Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.