research Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.
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research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization
FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
research Expression of AKT1 Along with AKT2 in Granulosa-Lutein Cells of Hyperandrogenic PCOS Patients
The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
research Androgen Receptors Are Only Present in Mesenchyme-Derived Dermal Papilla Cells of Red Deer Neck Follicles When Raised Androgens Induce a Mane in the Breeding Season
Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
research Androgen Receptor in Rat Liver: Characterization and Separation from a Male-Specific Estrogen-Binding Protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Lack of a Gonadal or Adrenal Androgenic Mechanism for the Hypertrichosis Produced by Diazoxide, Phenytoin, and Minoxidil
These drugs cause hair growth without affecting testosterone or adrenal hormones.
research Relationship Between Betacoronaviruses and the Endocrine System: A New Key to Understand the COVID-19 Pandemic—A Comprehensive Review
Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
research Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Inhibitory Effects of bFGF, VEGF, and Minoxidil on Collagen Synthesis by Cultured Hair Dermal Papilla Cells
bFGF, VEGF, and minoxidil decrease collagen production in hair cells, possibly affecting hair growth.
research An Important Role of Cutaneous Lymphatic Vessels in Coordinating and Promoting Anagen Hair Follicle Growth
Skin lymphatic vessels are essential for hair growth.
research The Modified Ferriman-Gallwey Score and Hirsutism Among Filipino Women
An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.
research Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory
The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
research Oral Glucose Tolerance Test Significantly Impacts the Prevalence of Abnormal Glucose Tolerance Among Indian Women With Polycystic Ovary Syndrome: Lessons From a Large Database of Two Tertiary Care Centers on the Indian Subcontinent
The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.
research Platelet-Rich Plasma: Applications in Dermatology
Platelet-rich plasma might help with skin aging, ulcers, and hair loss, but more research is needed to prove its effectiveness and safety.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research Hair Loss and Hirsutism in the Elderly
Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.
research Pharmacokinetic Parameters and Mechanisms of Inhibition of Rat Type 1 and 2 Steroid 5α-Reductases: Determinants for Different In Vivo Activities of GI198745 and Finasteride in the Rat
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research New Progesterone Esters as 5α-Reductase Inhibitors
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Thallium Poisoning
Thallium poisoning from contaminated tortillas caused severe symptoms and was mostly fatal or led to long-term health issues.
research A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia
Topical cetirizine improves hair density and thickness in androgenetic alopecia, but more research is needed.
research Evaluation of Cardiac Risk Marker Levels in Obese and Non-Obese Patients with Polycystic Ovaries
Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.
research Cross-Sex Hormone Therapy for Gender Dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and Literature Review of 13 Cases in Korea
First Korean case of Cronkhite-Canada syndrome with colon cancer and serrated adenoma.
research Testosterone Implants in Women: Pharmacological Dosing for a Physiologic Effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
research Disease Versus Disease: How One Disease May Ameliorate Another
Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.
research Testosterone Metabolism in Human Skin Cells In Vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
research Scleroderma and L-Tryptophan: A Possible Explanation of the Eosinophilia-Myalgia Syndrome
Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.
research Radioimmunoassay of Minoxidil in Human Serum
Minoxidil levels measured in human blood.