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TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.