October 2011 in “Iranian Journal of Dermatology” This study found that men with androgenic alopecia had significantly higher levels of lipoprotein (a), a risk factor for coronary artery disease, compared to men with normal hair.
January 2016 in “대한피부과학회지” This study observed no significant association between early-onset androgenetic alopecia and medical comorbidities in the Korean population.
16 citations
,
January 2010 in “Journal of Korean medical science/Journal of Korean Medical Science” This case report presents the first genetically confirmed case of acrodermatitis enteropathica in Korea, identifying compound heterozygous mutations in the SLC39A4 gene in an 8-month-old boy.
2 citations
,
May 2025 in “Frontiers in Pharmacology” In this study, analysis of FDA data revealed a substantial risk of dermatologic adverse events with aromatase inhibitors, especially anastrozole and exemestane, highlighting the importance of dermatologic monitoring during such therapies.
June 2026 in “Clinical Cosmetic and Investigational Dermatology” This case report found that a patient with ritlecitinib-resistant alopecia areata experienced significant recovery after 24 weeks of treatment with upadacitinib, highlighting its potential effectiveness and suggesting benefits of personalized treatment strategies targeting the JAK1-mediated pathway.
November 2022 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” In this study, the pi4kβ1β2 double mutant in Arabidopsis thaliana exhibited altered root growth, increased susceptibility to Blumeria graminis, and a potential correlation between PI4K activity and auxin response and immunity due to changes in vesicular trafficking and actin filaments.
November 2006 in “評価・診断に関するシンポジウム講演論文集” This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.
January 2017 in “Seoul National University Open Repository (Seoul National University)” This study found that the N-terminal fragment of AIMP1 enhances hair growth and proliferation of hair follicle stem cells in mice, suggesting its potential as a therapeutic peptide for hair loss treatment.
July 2025 in “SKIN The Journal of Cutaneous Medicine” This study describes characteristics and outcomes for adults initiating ritlecitinib for severe alopecia areata, highlighting increased hair regrowth and physician satisfaction with longer treatment durations, despite ongoing psychosocial impacts like embarrassment and anxiety among patients.
135 citations
,
March 2000 in “Journal of Biological Chemistry” This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.
January 2022 in “Al-Azhar Medical Journal” This study found a significant association between antigliadin antibodies (IgA and IgG) and alopecia areata severity, suggesting a need for celiac disease screening in these patients.
21 citations
,
November 2015 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses recent therapeutic approaches for alopecia areata, including the use of Janus kinase inhibitors and interleukin-2, and reports no new clinical results.
September 2024 in “Annals of Dermatology” This study established an IRGDS model with diagnostic capability for alopecia areata, which may serve as an auxiliary marker for the condition.
64 citations
,
November 2008 in “Journal of The American Academy of Dermatology” This study observed that acute diffuse and total alopecia, a subtype of alopecia areata, typically resolves rapidly and spontaneously within about six months, even without treatment, suggesting a favorable prognosis.
June 2023 in “International Journal of Research in Medical Sciences” This case report describes the first confirmed instances of X-linked adrenomyeloneuropathy/adrenoleukodystrophy in two brothers from Bangladesh, noting their progressive neurological symptoms, MRI findings, and differing disease outcomes over several years of observation.
1 citations
,
December 2023 in “Molecules/Molecules online/Molecules annual” This review summarized the latest knowledge suggesting that Janus kinase inhibitors may have therapeutic potential for treating skin diseases like atopic dermatitis and psoriasis, especially when conventional therapies do not work.
1 citations
,
January 1996 in “Springer eBooks” This article traces the origin of the term "androgenetic" and discusses the progressive nature of androgenetic alopecia with age, reporting no new research findings.
August 2021 in “Revista Colombiana de Reumatología/Revista Colombiana de Reumatologia” This case study reported that a 24-year-old patient with severe, treatment-resistant alopecia areata experienced excellent clinical improvement after one month of treatment with tofacitinib, a JAK inhibitor.
This study concluded that patients with alopecia areata receiving Janus kinase inhibitors are not maintaining the recommended frequency of lab monitoring every three months, indicating a need for new strategies to improve adherence.
September 2014 in “SciBX” In a mouse study, JAK inhibitors like Jakafi and Xeljanz prevented alopecia areata and aided hair regrowth; similar effects were observed in three patients with the condition.
April 2024 in “Expert opinion on investigational drugs” In this study, JAK inhibitors were reported as safe and effective treatments for moderate-to-severe chronic alopecia areata, although the appropriate duration of treatment remains uncertain, as stopping these medications often results in relapse.
December 2025 in “Journal of health economics and outcomes research” This analysis highlights the substantial financial burden AA creates in Saudi Arabia, emphasizing the importance of early diagnosis and standardized treatment protocols to improve resource allocation and patient outcomes.
April 2016 in “Journal of The American Academy of Dermatology” AGA patients have a lower quality of life than AA patients.
July 2017 in “Chinese Journal of Dermatology” This study concluded that a combination of three specific dermoscopy features provides the highest diagnostic value for distinguishing actinic keratosis from other facial lesions.
5 citations
,
December 2024 in “Anais Brasileiros de Dermatologia” This study outlines treatment options for alopecia, suggesting intralesional corticosteroids for localized adult cases and Janus Kinase inhibitors for severe cases, emphasizing a balance between hair regrowth rate and managing side effects.
29 citations
,
May 2016 in “Journal of the American Academy of Dermatology” This study observed that patients with alopecia areata had decreased odds of developing stroke and a potential decreased risk of acute myocardial infarction, though the latter was not statistically significant.
May 2026 in “Stem Cell Research & Therapy” In this study, researchers identified KRT6A as a potentially important gene in mesenchymal stem cell-derived treatments for alopecia areata, revealing its role as a diagnostic marker, predictor of disease severity, and a protective factor, with overexpression alleviating hair loss in experimental models.
June 2026 in “Frontiers in Immunology” In this case report, a 57-year-old man with severe atopic dermatitis, vitiligo, and alopecia areata showed rapid and significant improvement after treatment with the JAK1 inhibitor upadacitinib, suggesting its potential as an effective monotherapy for these co-existing conditions when conventional therapies fail.
10 citations
,
January 2010 in “Acta Histochemica Et Cytochemica” This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.
September 2020 in “Annals of Punjab Medical College” This study reports that pediatric alopecia areata in Faisalabad predominantly affects boys, often involves the scalp, and is significantly associated with family history of psoriasis and atopic disorders.