34 citations
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June 2011 in “Alcoholism: Clinical and Experimental Research” This study suggests that neurosteroids and compounds acting on GABA(A) receptors, like THIP, may modulate ethanol intake by influencing drinking patterns.
33 citations
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May 2006 in “Journal of Investigative Dermatology” This study found that high levels of parathyroid hormone-related protein expression can result in the production of shorter hair shafts, likely through effects on angiogenesis.
33 citations
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February 1996 in “Lancet” Losartan can cause temporary loss of taste.
24 citations
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September 2005 in “Journal of Cellular Biochemistry” This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.
9 citations
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March 1991 in “Endocrinology” This study in rats suggests that combining the 5 alpha-reductase inhibitor 4-MA with the antiandrogen Flutamide may enhance prostate cancer therapy by additively inhibiting prostatic growth and mRNA levels of androgen-sensitive prostatic binding proteins.
January 2026 in “Chonnam Medical Journal” Escin helps keep hair follicles in the growth phase longer.
December 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.
December 2025 in “BJPsych Open” This case study highlights an adolescent girl with atypical anorexia nervosa who experienced mental health changes after using semaglutide, underscoring the need for cautious prescription and follow-up of this medication to prevent adverse effects in vulnerable individuals.
January 2025 in “il Diabete” This study explores potential strategies for targeted drug delivery specifically to pancreatic beta-cells in type 2 diabetes treatment, highlighting methods for inducing drug expression in beta-cells, suitable drug carriers, active targeting peptides, and optimal administration routes.
September 2023 in “Journal of movement disorders” In this study, 27.9% of Parkinson's disease patients reported hair loss, with a higher incidence linked to a daily levodopa-equivalent dose over 448 mg, suggesting an association between dopaminergic medication use and hair loss complaints.
April 2019 in “Abstracts” This case study describes a rare presentation of childhood lupus with recurrent pericardial effusion and cardiac tamponade that responded to glucocorticoid therapy.
March 2017 in “Fundamental & Clinical Pharmacology” This case study reported an improvement in lower limb edema for a patient with type 2 diabetes mellitus after starting dulaglutide treatment, suggesting a potential role of the drug in sodium retention disorders.
January 2017 in “Elsevier eBooks” Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
This chapter reviews pharmacodynamic evaluations in endocrine disorders focusing on oral antidiabetics, insulin analogues, and hormone interactions, but reports no new results.
September 2012 in “The Egyptian Journal of Histology” In this study, flutamide at therapeutic doses caused significant histological changes in the testes and epididymis of adult albino rats, reducing androgen receptor immunoreactivity and increasing estrogen receptor immunoreactivity.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
October 2015 in “Annals of Internal Medicine” Dutasteride, fesoterodine, and finasteride help older patients with urinary issues.
July 2010 in “British Journal of Dermatology” This article discusses female pattern hair loss and explores potential causes beyond androgenic factors, reporting no new research findings.
118 citations
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May 2003 in “Toxicological Sciences” This study found that prenatal exposure to finasteride in rats led to permanent changes in developmental endpoints like anogenital distance and nipple retention, which were predictive of further reproductive tract malformations.
67 citations
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October 2005 in “Annals of Oncology” This review found that fulvestrant is well tolerated in postmenopausal women with hormone receptor-positive advanced breast cancer, showing lower incidence of joint disorders than non-steroidal aromatase inhibitors.
33 citations
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January 2002 This study found that daily topical application of 500 microg/ml latanoprost led to moderate to marked hair regrowth in a macaque model of androgenetic alopecia.
33 citations
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April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
31 citations
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January 2018 in “Pediatric annals” This article reviews the characteristics, diagnosis, and management of premature adrenarche and suggests it may predict future ovarian hyperandrogenism in some adolescents; no new clinical results are reported.
8 citations
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January 1987 in “Gynecological Endocrinology” This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.
1 citations
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July 2015 in “The European research journal” This case report describes reversible hair loss in a patient taking aripiprazole, suggesting this side effect may be common among psychotropic medications.
July 2026 in “Pharmacological Reports” In this pilot study, topical latanoprost acid was observed to increase hair count and improve hair follicle structure in women with androgenetic alopecia, with no serious adverse events, suggesting potential for further investigation to confirm its efficacy and safety.
November 2022 in “Journal of the Endocrine Society” This case study suggests that long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency, warranting further investigation.
January 2020 in “Journal of South Asian Federation of Obstetrics and Gynaecology” In this case study, laparoscopic bilateral salpingo-oophorectomy was associated with reduced androgen levels and partial reversal of male-pattern hair loss in a postmenopausal woman with ovarian hyperandrogenism.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
January 2016 in “Experimental Dermatology” This article in Experimental Dermatology does not include an abstract or any new research findings.