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Balding men have harder scalps.

This study explores how film, especially action movies, impacts teenagers' mentality, behavior, and socialization, highlighting its significant influence on both positive and negative developmental outcomes without established methods to mitigate adverse effects.

RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.

This study found that dominant mutations in the mouse agouti gene lead to maturity-onset obesity, with weight increases starting around 4 weeks and peaking between 8 and 17 months.

This study found that the prevalence of personality disorders in individuals with androgenetic alopecia was significantly higher than in the general population, irrespective of gender.

In this study of captive rhesus macaques, social hair plucking was related to kinship, showed characteristics of both prosocial and aggressive behaviors, and was associated with alopecia and hair cortisol concentrations in females.

This study of androgenic alopecia patients reports that stress was associated with AGA in both men and women, with notable findings differing by gender, age, and AGA type.

This article reviews studies on younger men using finasteride for hair loss, finding persistent sexual and nonsexual side effects like erectile dysfunction and depression, and reports lower neurosteroid levels in affected individuals.

This study discusses a hypothesis for repurposing non-cancer drugs and combining micronutrients to target cancer and cancer stem cells with fewer side effects, suggesting a potential new approach for more effective cancer therapy.

This review discusses the current therapeutic options for female pattern hair loss and emphasizes the need for managing patient expectations of permanent regrowth, reporting no new clinical results.

The EPICAP study aims to investigate various factors influencing prostate cancer, including circadian disruption, inflammation, hormonal and metabolic factors, and genetic susceptibility, and reports no new clinical results.

This study found that pentoxifylline plus topical corticosteroids had the highest treatment success rate for alopecia areata compared to no treatment, but the best overall treatment remains uncertain due to varying data.

In this animal study, finasteride significantly improved autism-like symptoms in rats by reversing biochemical markers and enhancing behaviors, potentially due to its antioxidant and anti-androgen effects.

This article discusses the challenges and considerations in drug repurposing, particularly the importance of dose finding studies when adapting drugs for new indications, and reports no new clinical results.

In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.

This study found that arginine vasotocin is evolutionarily conserved across diverse taxa and may play roles in neuroendocrine, immune, and stress signaling, with potential antimicrobial applications.

In this study, high-dose oral administration of Ramania leaf ethanol extract in Wistar rats resulted in no significant acute toxicity symptoms, though gastric ulcers and hair loss were observed. The extract is classified as non-toxic under specified guidelines, with an LD50 greater than 5000 mg/kg.

In this study, deep learning models accurately predicted gene expression in whole slide images of colorectal cancer, with convolutional neural networks outperforming transformer and graph-based approaches in spatial RNA pattern prediction.

Hair shaft miniaturization leads to hair follicle stem cell loss, suggesting Piezo1 as a potential treatment target.

This study found that generalized anxiety disorder symptoms predicted higher emotional distress and hair cortisol concentration, with dominance unexpectedly increasing the impact of anxiety on hair cortisol.

This case report describes a 4-year-old boy with autism and a rare condition causing precocious puberty, where treatment for hyperandrogenism unexpectedly intensified his aggressive behavior.

This study found that full-length Agouti protein modulates melanocortin receptor signaling through a dual mechanism involving competitive antagonism and receptor down-regulation, whereas the carboxyl-terminal fragment acts solely as a competitive antagonist.

This study reports that Korean adolescents with androgenetic alopecia tend to have milder symptoms than adults and a higher prevalence of family history of alopecia.

This study found that changes in the expression of the Agouti gene contribute to the pale pigmentation in beach mice, with implications for melanocyte development and localization.

This study found that personality disorders, more than gender, were associated with psychopathologic reactions to androgenetic alopecia.

This study explores the neurobiology and genetics of barbering (hair and whisker biting) in laboratory rodents, and its potential links to stress, aggression, grooming, and stereotypic behaviors, highlighting its significance in experimental work with these animals.

This study reports that in ovarian high-grade serous carcinoma, overexpressed S100A4 likely promotes epithelial-mesenchymal transition and cancer stem cell properties, affecting tumor behavior through its interaction with NMIIA and mutant p53.

This study reported that patients with acanthosis nigricans and insulin resistance exhibited higher insulin levels and were associated with increased insulin resistance correlating with serum testosterone levels.

This study found that rare germline pathogenic variants in BRCA2, BRCA1, and ATM are associated with increased risk of aggressive prostate cancer.

The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.