Drug Repurposing: A Novel Strategy to Target Cancer Stem Cells and Therapeutic Resistance

The document discussed the limitations of chemotherapy in cancer treatment, highlighting its inability to guarantee a complete cure and its severe adverse effects. It emphasized the role of cancer stem cells in disease progression, drug resistance, and recurrence, necessitating novel strategies for cancer management. The paper proposed drug repurposing, which involves screening non-cancerous drugs for anticancer activity, as a promising alternative due to the adverse effects of existing anticancer drugs. Additionally, it explored the potential of micronutrients, known for their significant anticancer effects and minimal side effects, in cancer therapy. The combination of drug repurposing and micronutrients targeting cancer and cancer stem cells was suggested as a potentially effective therapeutic approach for better tumor growth control.