Growing Up Fast: Managing Autism Spectrum Disorder and Precocious Puberty

    September 2020 in “ Journal of developmental and behavioral pediatrics/Journal of developmental & behavioral pediatrics ”
    Abigael E. Finkle, Samantha Zavertnik, Susan E. Myers, DePorres Cormier, Jennifer L. Heithaus, Marilyn Augustyn
    TLDR The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.
    John, a 4-year-old boy with autism spectrum disorder (ASD) and developmental delay, exhibited aggressive behavior and signs of precocious puberty, including rapid growth and elevated testosterone levels. Genetic testing identified a rare condition, Familial Male-Limited Precocious Puberty (FMPP), as the cause. Despite starting off-label therapy with bicalutamide and anastrazole, his aggression intensified. The case highlights the complexity of managing co-occurring ASD and precocious puberty, particularly when treatment for one condition exacerbates symptoms of the other.
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