research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
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research Practical Geriatrics: Maintaining Sexual Health After Menopause
Maintaining sexual health after menopause is possible with patient approaches, hormone supplements, and therapy, despite needing more research.
research The Rotterdam Study: 2016 Objectives and Design Update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research Hormone Replacement Therapy and the Skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Group-ICA Model Order Highlights Patterns of Functional Brain Connectivity
Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.
research Diagnosis, Manifestations, Laboratory Investigations, and Prognosis in Pediatric and Adult Cushing’s Disease in a Large Center in China
Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Abstract Presented at the Joint Meeting of the 21st Meeting of the Japanese Research Society of Clinical Anatomy and the 6th Meeting of the Society for Aging Imaging
High-resolution imaging is crucial for diagnosing and planning treatments in clinical anatomy and aging.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
research Decision Letter: Quantitative Mapping of Human Hair Greying and Reversal in Relation to Life Stress
Hair can naturally regain color, and stress might influence greying and its reversal.
research Author Response: Quantitative Mapping of Human Hair Greying and Reversal in Relation to Life Stress
Hair can naturally regain color after greying, and this change may be linked to stress levels.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Regulation of the Wound Healing Response During Aging
Aging slows wound healing due to weaker cells and immune response.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research Light Pollution and Oxidative Stress: Effects on Retina and Human Health
Excessive blue light harms eye cells and disrupts sleep patterns.
research Melatonin: Functions and Ligands
Melatonin helps regulate sleep and may aid in treating various health issues.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation
Human skin xenografting could improve our understanding of skin development, renewal, and healing.
research Lifestyle Drugs in Old Age: A Mini-Review
Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.
research Age-Associated Inflammation Inhibits Epidermal Stem Cell Function
Aging causes skin stem cells to work less effectively.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research Age, Health, and Attractiveness Perception of Virtual Human Hair
Hair style affects perceptions of age, health, and attractiveness more than hair color does.
research Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia
Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
research Metabolism of Finasteride in Rat Hepatic Microsomes: Age and Sex Differences and Effects of P450 Inducers
Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.
research Why Some Women Look Young for Their Age
Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
research Effects of Strain and Age on Ear Wound Healing and Regeneration in Mice
Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research A Holistic Approach to Antiaging as an Adjunct to Antiaging Procedures: A Review of the Literature
Combining cosmetic procedures with lifestyle changes improves antiaging results.
research Skin Aging and Menopause: Implications for Treatment
Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.