July 2022 in “Journal of Cosmetic Dermatology” This study found that in patients with frontal fibrosing alopecia, combining topical tacrolimus with isotretinoin is more effective after four weeks of treatment compared to tacrolimus with finasteride, though both regimens offered some benefit.
10 citations
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November 2021 in “PLoS ONE” This study suggests that the T allele of the SNP rs2476601 in the PTPN22 gene may increase the risk of alopecia areata, although further studies are necessary to validate this finding across different populations.
August 2018 in “Journal of the American Academy of Dermatology” Tofacitinib is a potential alternative treatment for alopecia totalis, especially in patients with a shorter duration of the condition and more preserved hair follicles, but the overall response rate is low.
In this narrative review, researchers evaluated existing literature on the treatment of frontal fibrosing alopecia, finding that while no curative treatment exists, clinical improvements can be achieved through personalized and combined therapy approaches.
January 2026 in “Elsevier eBooks”
11 citations
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January 2018 in “Acta dermato-venereologica” In this study, oral tofacitinib showed higher efficacy and tolerability in treating refractory alopecia totalis and universalis compared to traditional treatments, achieving a 50% improvement in severity scores for 44.4% of patients over six months, with fewer adverse effects.
February 2011 in “Journal of the American Academy of Dermatology” This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal women in Algeria.
August 2020 in “OPAL (Open@LaTrobe) (La Trobe University)” This article offers dermoscopic comparisons between fibrosing alopecia and androgenetic alopecia with seborrheic dermatitis but reports no new research findings.
30 citations
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March 2011 in “Australasian Journal of Dermatology” This case report found that a woman's hair loss, which progressed while using spironolactone and topical minoxidil, reversed after switching to flutamide therapy.
3 citations
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November 2020 in “Clinical, Cosmetic and Investigational Dermatology” This review summarizes the current treatment modalities for frontal fibrosing alopecia and provides a practical guide for clinicians, but reports no new clinical results.
6 citations
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July 2004 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This case report documents two postmenopausal women with frontal fibrosing alopecia whose hair loss stabilized after treatment with topical corticosteroids, one also using minoxidil.
16 citations
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January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This case study discusses a postmenopausal woman's frontal fibrosing alopecia and lichen planus pigmentosus, controlled with corticosteroids and finasteride, highlighting diagnostic and therapeutic challenges in scarring alopecia.
January 2025 in “Revista del Centro Dermatológico Pascua” Early diagnosis and treatment can help manage fibrosing alopecia in older women.
August 2026 in “ACTA MEDICA IRANICA” This study found that women with female pattern hair loss exhibited hormonal imbalances, with the Free Androgen Index being a particularly effective diagnostic marker.
30 citations
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November 2008 in “Facial Plastic Surgery” This review discusses hair transplant techniques for female pattern hair loss and reports no new clinical results; it highlights the benefits of transplants combined with various treatments for improved hair density and styling options.
7 citations
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August 2021 in “Journal of the European Academy of Dermatology and Venereology” This study suggests that early initiation of treatment in fibrosing alopecia in a pattern distribution may lead to a more favorable outcome, as evident in some patients experiencing arrested disease progression and hair regrowth.
2 citations
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May 2017 in “Journal of the American Academy of Dermatology” This study observed that antifungal treatment in fungal asthma patients led to a significant decrease in oral corticosteroid use, though the clinical importance remains unclear due to potential confounders.
2 citations
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November 2007 in “Hair transplant forum international” This abstract introduces the concept of follicular units (FUs) in the human scalp but presents no new research findings.
5 citations
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February 2015 in “Dermatologica Sinica” In this study, a computer-aided imaging system accurately measured the width of balding areas in female pattern hair loss, correlating strongly with clinical staging severity.
January 2024 in “JEADV clinical practice” This article reviews how SALT scores are used in clinical trials for alopecia areata and provides patient images to help clinicians understand and apply these scores in practice; it reports no new clinical results.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study revealed that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by modulating the linoleic acid metabolism-Mg2+ pathway, providing new insights for potential treatments and diagnosis.
23 citations
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June 1950 in “American journal of diseases of children” This article discusses the interest in folic acid antagonists for leukemia treatment, noting their potential mechanism of interfering with cellular growth, but reports no new clinical results.
1 citations
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August 2023 in “International Journal of Surgery Case Reports” In this study, free flaps, specifically the ALT-free tissue transfer, were found to be safe and reliable for reconstructing large scalp defects requiring both scalp and skull repairs, with consistent results observed in clinical applications.
This study found that patients with frontal fibrosing alopecia showed significant alterations in protein expression in forehead corneocytes, suggesting the condition may have systemic implications beyond the scalp.
November 2024 in “Skin Appendage Disorders” In this study, researchers assessed the quality of life in patients with different types of alopecia using the Skindex-29 and DLQI questionnaires, finding that telogen effluvium and alopecia areata had the greatest pretreatment impact on quality of life, with moderate responsiveness observed after treatment.
3 citations
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October 2020 in “UNC Libraries” This article discusses the SLICC's revision and validation of the ACR SLE classification criteria to enhance clinical relevance and integrate recent immunological insights, but does not report new clinical results.
1 citations
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January 2012 in “Zhongguo shiyan fangjixue zazhi” This study found that adding Kang'ai injection to FLO chemotherapy for advanced gastric cancer improved clinical outcomes and quality of life while reducing side effects, compared to FLO chemotherapy alone.
4350 citations
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May 2012 in “Arthritis & Rheumatism” This study found that the new SLICC classification criteria for systemic lupus erythematosus were more sensitive and resulted in fewer misclassifications than the current ACR criteria, although they had lower specificity.
8 citations
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August 2017 in “Skin appendage disorders” Red dots on the upper chest may be an early sign of certain types of hair loss.