Visualizing Severity Of Alopecia Tool Scores In The Clinical Setting Using Patient Images From A Clinical Trial

    January 2024 in “ JEADV clinical practice
    Natasha Atanaskova Mesinkovska, Brett King, Sergio Vañó‐Galván, Yutaka Shimomura, Jakub Jedynak, Jill Shwed McCollam, Evangeline Pierce, Amy K. Ellinwood, Rodney Sinclair
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Baricitinib →

    JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

    Image
    Studysummary This article reviews how SALT scores are used in clinical trials for alopecia areata and provides patient images to help clinicians understand and apply these scores in practice; it reports no new clinical results.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study used images from the BRAVE-AA1 clinical trial, which included 722 patients with severe alopecia areata (AA), to demonstrate the application of the Severity of Alopecia Tool (SALT) scores in a clinical setting. The images, showing a range of SALT scores (0-100), illustrated hair regrowth progression in patients treated with baricitinib over 52 weeks. This visual approach helps clinicians understand and apply SALT scores for assessing disease severity and monitoring treatment response, aiding in treatment decisions and identifying patients for systemic therapies. However, the study notes limitations such as inter-rater variability and the inability of photographs to capture changes in hair density or active shedding.
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