October 2024 in “Zagazig University Medical Journal” This clinical trial found that transdermal delivery of 5-Fluorouracil using fractional CO2 laser resulted in a significantly better treatment response in alopecia areata patients compared to intralesional injections of the same drug, with a greater reduction in the Severity of Alopecia Tool Score.
17 citations
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August 2002 in “Dermatologic Surgery” This study found that topical fluridil increased the anagen hair percentage in men with androgenetic alopecia without causing irritation or systemic absorption over 9 months.
4 citations
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” In this study, the 308-nm excimer lamp was reported to be a safe alternative treatment for alopecia areata, with a 41.1% overall response rate and a 50% response rate in severe cases.
1 citations
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January 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study found that treating patchy alopecia areata with fractional CO2 laser and topical triamcinolone acetonide was more effective and safer than intralesional triamcinolone, despite higher initial discomfort, as it resulted in greater patient satisfaction and fewer adverse effects like skin atrophy.
August 2021 in “Journal of advances in medicine and medical research” In this study, both excimer light and low level light therapy were found to be safe and effective for treating alopecia areata, with excimer light showing better and more sustained improvement.
31 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the use of the Nd:YAG laser for hair removal and reports no new research findings.
January 2022 in “Al-Azhar Medical Journal” This study found a significant association between antigliadin antibodies (IgA and IgG) and alopecia areata severity, suggesting a need for celiac disease screening in these patients.
1 citations
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July 2024 in “Journal of lasers in medical sciences” This case study reports that treating a female patient with facial partial unilateral lentiginosis using a 532-nm Nd:YAG fractional picosecond laser resulted in significant improvement in pigmentation without notable side effects, indicating it may be an effective and well-tolerated treatment option.
85 citations
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November 2004 in “Journal of the American Academy of Dermatology” The 308-nm excimer laser helps hair regrowth in some alopecia areata cases but not all.
2 citations
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January 2013 in “International Journal of Dermatology” ALDOA levels drop in hair cells during hair loss.
6 citations
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September 2019 in “Journal of Cosmetic Dermatology” In this study, patients with androgenic alopecia who underwent 10 sessions of 1540-nm fractional erbium glass laser treatment over 5 months experienced significant improvements in hair density and thickness, with no major safety concerns reported.
1 citations
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September 2021 in “Journal of The American Academy of Dermatology” This study observed that inflammation in androgenetic alopecia samples was similar to alopecia areata controls, but infundibular and isthmic inflammation were significantly more common in androgenetic alopecia cases.
3 citations
,
September 2001 in “Dermatologic Surgery” This study found that adding a 5 W CO2 laser to an Er:YAG laser improved hemostasis without significantly affecting mean hair counts or increasing lateral thermal damage in men with androgenetic alopecia.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Abatacept may help some people with alopecia areata regrow hair.
1 citations
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September 2001 in “Dermatologic Surgery” This study found that adding a low-power CO2 laser to Er:YAG laser improves hemostasis in hair transplantation without significantly affecting hair counts or increasing thermal damage.
July 2024 in “Journal of Investigative Dermatology” The Fas/FasL pathway may play a role in alopecia areata.
September 1998 in “Journal of the European Academy of Dermatology and Venereology”
5 citations
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July 2023 in “International Journal of Women’s Dermatology” This study reports that anifrolumab showed promising improvement in a case of refractory discoid lupus erythematosus, specifically enhancing skin lesions and promoting hair regrowth, suggesting potential as an effective therapy for severe cases.
September 2023 in “Journal of the American Academy of Dermatology” This study examined the application of new clinical guidelines for diagnosing frontal fibrosing alopecia in 18 men, highlighting that current diagnostic criteria may often overlook early beard involvement and sideburn recession.
5 citations
,
June 2023 in “Engineering Technology & Applied Science Research” This study developed a new neural network model (AA-GAN-AB-MTEDeep) to enhance Alopecia Areata classification using synthetic scalp images, achieving an accuracy of 96.94%.
September 2024 in “Egyptian Journal of Dermatology and Venerology” This study found that intralesional injection of triamcinolone acetonide combined with latanoprost (a PGF2α analog) was more effective in treating localized alopecia areata, showing higher treatment response rates and greater reduction in severity scores compared to other treatments.
September 2014 in “Chinese Journal of Dermatology” In this study, several dermoscopic features such as hair diameter diversity, brown peripilar sign, and focal atrichia were frequently observed in both male and female androgenetic alopecia patients, highlighting these as potential AGA indicators.
September 2021 in “Medical lasers” Laser treatment followed by a special hair growth solution increased hair count and thickness without side effects.
October 2024 in “Journal of Pakistan Association of Dermatologists” This study found that intralesional triamcinolone was more effective than the 308 nm Excimer laser in achieving >75% hair regrowth in patients with localized alopecia areata over 12 weeks.
This review emphasizes the importance of accurately distinguishing between diffuse alopecia areata and telogen effluvium in dermatological practice due to differing treatment implications and long-term patient expectations, but reports no new clinical results.
47 citations
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October 2016 in “Molecular and Cellular Endocrinology” This study found that DKK1 and WNT10b are paracrine factors that modulate hair follicle stem cell differentiation inhibition, contributing to androgenetic alopecia by affecting Wnt signaling in androgen-sensitive dermal papilla cells after dihydrotestosterone stimulation.
13 citations
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January 2013 in “International Journal of Trichology” This study found that androgenetic alopecia patients showed significantly higher perifollicular lymphocytic inflammation and fibrosis compared to controls, emphasizing the need for histopathological evaluation during hair transplantation.
16 citations
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July 2018 in “Dermatologic Surgery” In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.
This study found that home use of low-level light therapy reduced inflammation and symptoms like itching and burning in women with frontal fibrosing alopecia over six months.
May 2025 in “Journal of Nanobiotechnology” This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.