August 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that combining microneedling at depths of 0.5 mm or 1 mm with minoxidil tincture significantly improved hair density and diameter in men with androgenetic alopecia compared to minoxidil alone, although the deeper microneedling also led to higher adverse reactions.
55 citations
,
July 2013 in “Dermatologic therapy” This review explores the impact of various medications on male fertility, highlighting reversible negative effects from methotrexate, finasteride, and ketoconazole, while reporting no adverse fertility effects for oral retinoids and certain immunosuppressants.
31 citations
,
April 2019 in “Experimental and Therapeutic Medicine” This review focuses on the immunologic-based skin conditions that can result from β-blocker use, emphasizing potential adverse dermatologic effects rather than their therapeutic benefits.
15 citations
,
January 2020 in “BioMed Research International” In this study of patients with androgenetic alopecia, botulinum toxin type A was found to significantly increase hair counts and improve hair density and coverage, with enhanced results observed when combined with oral finasteride, revealing a safe and effective treatment approach without adverse effects.
3 citations
,
August 2000 in “Anatomia Histologia Embryologia” In this study, prenatal exposure to a non-teratogenic dose of all-trans-retinoic acid showed no adverse effects on vibrissal follicle development in NMRI mice.
2 citations
,
April 2019 in “Proceedings of Singapore Healthcare” This study found that a collaborative care model in rheumatoid arthritis clinics improved nb-DMARD dose optimization, adherence to monitoring guidelines, and detection of related adverse drug events compared to standard care.
1 citations
,
October 2023 in “Animals” This study found that supplementing raccoon dogs' diets with 0.25 g/kg Platycladus orientalis leaf extract improved growth performance and altered intestinal microbiota, but higher doses may have adverse effects.
1 citations
,
January 2022 in “Annals of Dermatology” In this South Korean retrospective study, dutasteride improved hair growth more effectively than finasteride in men with androgenic alopecia, and had a similar or possibly lower rate of adverse events, suggesting it as a viable treatment option.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a comprehensive Ayurvedic treatment protocol was shown to effectively improve symptoms of Indralupta, a condition similar to alopecia areata, by reducing patch size, increasing hair density, and restoring follicular activity, without adverse effects.
December 2025 in “The International Journal of Medical Science and Health Research” This literature review explored the potential of Rosmarinus Officinalis as a plant-based solution for Androgenetic Alopecia, highlighting its effectiveness and minimal side effects compared to conventional treatments, which often have significant adverse effects.
December 2025 in “Journal of Pharmacy And Bioallied Sciences” In this case study, Ayurvedic management including Viddhakarma and Nilibhringadi Taila led to significant hair regrowth and improved hair quality in a 37-year-old man with androgenetic alopecia, without adverse effects.
June 2024 in “Georgetown medical review” This article evaluated evidence on finasteride's effects on male reproductive health, finding contradictory data about its adverse effects, but consensus that such cases are infrequent in research and clinical settings.
May 2024 in “Lasers in medical science” In this retrospective study, a combined therapy of ablative fractional Er: YAG laser and medication was more effective in treating male androgenetic alopecia than medication alone, without causing serious adverse effects, as evaluated over 24 weeks.
March 2024 in “Journal of Evidence-Based Integrative Medicine” This study found that a hair tonic containing 1% teak leaf extract significantly increased hair growth and user satisfaction in men with androgenic alopecia after 24 weeks, without causing adverse effects, and was comparable to the standard treatment, minoxidil.
September 2023 in “International Journal of Cosmetic Science” The researchers observed that two non-antimicrobial shampoos caused a significant increase in fungal germs but did not affect the overall scalp microbiota diversity over two weeks, suggesting these formulations may preserve or stimulate the scalp microbiota without adverse effects.
August 2023 in “Dermatology and Therapy” This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.
July 2023 in “Fayoum University Medical Journal” This study evaluated minoxidil at different concentrations and found it effective in treating androgenetic alopecia when used with Dermapen injectors, noting mild adverse effects that patients tolerated well, and recommended dermoscopy for early diagnosis and treatment monitoring.
This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.
January 2023 in “Journal of cosmetic dermatology” This study concluded that fractional laser therapy, alone or combined with minoxidil or cortisol, effectively treated alopecia areata, showing better outcomes than the drugs alone, without increasing adverse effects, though effectiveness did not significantly differ from similar physical treatments.
March 2026 in “Cancer Diagnosis & Prognosis” In this study, researchers used a patient-reported outcome questionnaire to assess long-term adverse effects in breast cancer patients undergoing chemotherapy, finding persistent symptoms like neuropathy, dysgeusia, insomnia, and nail loss. Peripheral neuropathy was notably prolonged in those receiving anthracycline- and taxane-based regimens compared to docetaxel/cyclophosphamide.
January 2025 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” This study in a real-world setting found that baricitinib was effectively reducing disease severity in severe alopecia areata patients over 52 weeks, with 37.20% of participants achieving significant improvement and 72.40% experiencing mild or no adverse events.
January 2025 in “American Journal of Translational Research” This study reported that the combination of EE-CPA and raloxifene effectively manages PCOS-related infertility, enhancing pregnancy outcomes through improvements in metabolism, sex hormones, ovarian function, and endometrial receptivity, without significantly increasing adverse effects.
April 2024 in “MRIMS journal of health sciences” This study observed that autologous growth factor concentrate combined with topical minoxidil significantly improved hair growth and patient satisfaction in individuals with androgenic alopecia, with no adverse effects reported.
January 2011 in “The Internet Journal of Pharmacology” This paper reviews Minoxidil's use for baldness treatment but reports no new findings; it also raises questions on its efficacy, permanence, cost-effectiveness, demographic benefit, and potential adverse effects.
January 1972 in “Open PRAIRIE (South Dakota State University)” This research explored potential mechanisms for the toxicity of mimosine but did not identify a conclusive reason for its adverse effects.
April 2023 in “Journal of Shaheed Suhrawardy Medical College” This study observed that platelet-rich plasma therapy significantly improved hair density and diameter in patients with androgenetic alopecia, with no treatment-related adverse effects reported.
August 2020 in “Asian Pacific Journal of Cancer Prevention” This commentary discusses a study on the long-term effects of finasteride in Saudi women, noting adverse effects but also raises concerns about sample limitations, emphasizing its potential as a basis for further research.
July 2020 in “Journal of Cosmetic and Laser Therapy” This study found that platelet-rich plasma injections significantly increased hair density and width while improving patient satisfaction in androgenic alopecia treatment without adverse effects.
27 citations
,
November 1998 in “Journal of Endocrinological Investigation” This study reported that 6 months of finasteride treatment significantly improved idiopathic hirsutism in women, with benefits persisting 6 months post-treatment and no adverse reactions observed.
5 citations
,
November 2016 in “Experimental and Therapeutic Medicine” In this study, BeauTop treatment significantly increased hair growth in people with androgenetic alopecia compared to placebo, showing effectiveness without adverse reactions.