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Dextran sulfate was found to be toxic and ineffective for treating HIV.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

New treatments for male hypogonadism are effective and should be personalized.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

Finasteride may help treat chronic CSC, improving vision.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Hormonal therapies are safe and effective for treating adult women's acne.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Prolactin may be important for skin growth and immune function.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.