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Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Androgens can both increase and decrease hair growth in different parts of the body.

Hair loss increases with age; alcohol raises risk, more female partners lowers it.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Minoxidil may cause heart issues in animals and humans.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Mutations in certain receptors can cause diseases and offer new treatment options.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

A new side effect of aromatic retinoid treatment is soft nails.