18 citations,
December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.
27 citations,
December 2013 in “Endocrinology” Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
16 citations,
August 1967 in “JAMA” Oral contraceptives may cause hair loss in women.
187 citations,
January 1994 in “The New England Journal of Medicine” Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
49 citations,
June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
4 citations,
January 2015 in “Endocrinology & metabolic syndrome” Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.
59 citations,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
48 citations,
January 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
37 citations,
November 1995 in “Journal of Investigative Dermatology” Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
25 citations,
January 2000 in “Hormone Research in Paediatrics” Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
21 citations,
June 2005 in “Alcoholism: Clinical and Experimental Research” Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
9 citations,
January 1978 in “Australian Journal of Biological Sciences” Flumethasone causes wool shedding in Merino wethers, with recovery in about 60 days.
January 2018 in “Springer eBooks” The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.
85 citations,
June 2008 in “Annals of the New York Academy of Sciences” PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.
75 citations,
March 1999 in “Fertility and sterility” Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
72 citations,
January 2003 in “American Journal of Pathology” A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
66 citations,
January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
63 citations,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
56 citations,
October 2018 in “Journal of The American Academy of Dermatology” Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
42 citations,
July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
41 citations,
November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
34 citations,
July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
26 citations,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
11 citations,
January 2007 in “Veterinary dermatology” Fulvestrant at 10 mg/kg does not promote hair regrowth in dogs with alopecia X.
March 2024 in “International journal of pharmaceutical sciences and drug research” Androgenetic alopecia is influenced by various factors and can be treated with medications, procedures, and non-drug methods.
September 2023 in “Journal of Rawalpindi Medical College/Journal Rawalpindi Medical College” Birth control pills with cyproterone acetate and drosperinone can reduce excessive hair growth in women with PCOS, but they may not be right for everyone.
December 2018 in “IntechOpen eBooks” Neurohormones help control skin health and could treat skin disorders.
205 citations,
July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
60 citations,
September 2001 in “Journal of the American Academy of Dermatology” Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
60 citations,
June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.