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11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Skin aging reflects overall body aging and can indicate internal health conditions.

ADAM17 could be a potential target for treating PCOS.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

Hutchinson-Gilford Progeria Syndrome causes rapid aging from a genetic mutation, with no cure but ongoing research into potential treatments.

Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.

The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Inositol was more effective than Metformin in treating symptoms of PCOS in women.

Inositol was more effective than metformin in improving menstrual cycles and pregnancy rates in PCOS patients.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Found new possible treatments for hair loss.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.