research MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes
Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
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research The Frequency of Alopecia and Quality of Life in High-School Students in Rural Areas of Eskisehir
Hair loss was found in 37.4% of surveyed rural high-school students in Eskisehir, Turkey, affecting their quality of life, especially in general health and mental well-being.
research Autoimmune Skin Disorders
The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.
research Impact of Microbial Infection on Sperm Parameters of Seminal Bacteria in Asymptomatic Subfertile Males
Seminal bacteria can lower sperm quality in subfertile men.
research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research Ginseng Phytochemicals as Therapeutics in Oncology: Recent Perspectives
Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
research Mechanisms Underlying Select Chemotherapeutic-Agent-Induced Neuroinflammation and Subsequent Neurodegeneration
Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
research Treatment Pearls From Europe
European dermatologic treatments focus on lifestyle and psychosocial factors, use diverse methods like baths and climate therapy, and emphasize the importance of diet and supplements for skin health.
research Follicle Hormones
Follicle Stimulating Hormone is important for fertility.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Ganoderma Lucidum Extract Attenuates Corticotropin-Releasing Hormone Induced Cellular Senescence in Human Hair Follicle Cells
Ganoderma lucidum extract may help treat stress-related hair loss.
research An Overview of Harmful Effects of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) can lead to diabetes, heart disease, cancer, and mental health problems.
research A Review on the Chemical Constituents and Pharmacological Efficacies of Lindera Aggregata (Sims) Kosterm
Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
research Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ
Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2
Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Anti-Androgenic Activity of Myricae Cortex: Isolation of Active Constituents from Bark of Myrica Rubra
The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.
research Germacrene Analogs Are Anti-Androgenic on Androgen-Dependent Cells
Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
research Isolation and HPLC Quantitative Determination of 5α-Reductase Inhibitors from Tectona Grandis Leaf Extract
Teak leaf extract contains compounds that could help treat hair loss.
research Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract
Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Anti-Androgenic Effect of Sesquiterpenes Isolated from the Rhizomes of Curcuma Aeruginosa Roxb.
Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
research Role of 5 Alpha-Reductase Inhibitors in the Management of Prostate Cancer
5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Clinical Trial and In Vitro Study Investigating Topical Application of Zataria Multiflora Boiss. and Matricaria Chamomilla Extracts for Androgenetic Alopecia
Extracts improve hair growth in alopecia.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson's Disease Models
Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.