16 citations
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August 2022 in “Nature Communications” In this study, researchers discovered that ROR2, a Wnt receptor, plays a crucial role in regulating hair follicle stem cell self-renewal and maintenance, compensating for the absence of β-catenin.
13 citations
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December 2020 in “Dermatologic Therapy” This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.
13 citations
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February 2018 in “Plastic and Reconstructive Surgery” The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
12 citations
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July 1957 in “Journal of Investigative Dermatology” This historical observation found that parathyroid extract treatment in newborn rats led to a condition resembling scleroderma, characterized by skin hardening, calcium deposition, and possible necrosis.
11 citations
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October 2003 in “Postgraduate Medical Journal” This study described four cases of delayed diagnosis of Cushing’s syndrome, highlighting that increased clinical awareness and screening could reduce its associated morbidity and mortality.
9 citations
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August 2002 in “Current Opinion in Pediatrics” This article discusses the roles of pediatrics and dermatology departments at Yale University School of Medicine, but reports no specific clinical results.
8 citations
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September 2017 in “Journal of Investigative Dermatology” This study found that inhibiting the interaction between CXXC5 and Dishevelled could stimulate hair regrowth in mouse models by enhancing WNT/β-catenin signaling, suggesting a potential therapeutic strategy for hair loss involving compounds that block this interaction, such as interfering short peptides.
6 citations
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October 2015 in “Clinical Case Reports” This study highlights that scalp hair loss is an underreported side effect of somatostatin analogs therapy, potentially linked to decreased GH/IGF-1 levels or a direct drug effect.
6 citations
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August 2005 in “The Journal of Clinical Endocrinology & Metabolism” This study found that finasteride treatment in benign prostatic hyperplasia patients induced a transient, caspase-dependent apoptosis in epithelial cells, with activity peaking at 6-8 days and diminishing by 27-32 days.
3 citations
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October 2018 in “Experimental and Therapeutic Medicine” In this study, researchers found that discontinuing tamsulosin for one month before cataract surgery in rats reduces manifestations of intraoperative floppy iris syndrome, suggesting alternative preoperative treatments may be beneficial.
3 citations
,
November 2014 in “Protein Expression and Purification” This study reported successful recovery of biologically active recombinant murine Wnt3a without detergent, suggesting usefulness for structure-activity studies avoiding detergent-related issues.
2 citations
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May 2006 in “Women's Health Medicine” This article provides an overview of ovulation disorders, discussing ovarian, hypothalamic, and endocrine defects but reports no new clinical findings.
2 citations
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January 1992 in “Neurologia medico-chirurgica” This study describes a new radiation method called three-dimensional moving field radiation therapy, which showed improved tumor targeting and reduced damage to surrounding tissues compared to traditional one-plane methods.
1 citations
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February 2025 in “Journal of Endocrinological Investigation” This review discusses the prevalence and clinical impact of menstrual abnormalities, acne, and hirsutism in young women with Cushing's syndrome and reports no new clinical results.
1 citations
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August 2024 in “Transgenic Research” In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.
1 citations
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January 2006 in “Elsevier eBooks” The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
This study reports that in Rex rabbits, age affects fur quality and hair follicle traits, with the Wnt signaling pathway playing a role in their periodic hair follicle development.
November 2024 in “Malaysian Journal of Microbiology” In this study, researchers found varying levels of multiple autoantibody types among thyroid disorder patients, with 84.84% of those with immunological hypothyroidism reporting symptoms like weight gain and lethargy, whereas 81.81% of those with immune hyperthyroidism experienced hair loss.
September 2024 in “Brazilian Journal of Case Reports” In this case study, a 62-year-old woman with severe hyperandrogenism underwent a clomiphene test, which suggested an ovarian origin for her condition, leading to the discovery of a Leydig cell tumor after a bilateral oophorectomy.
February 2024 in “Cureus” This study presented an elderly male with a nodular lesion diagnosed as pilomatricoma and discussed the value of diagnostic tools like dermoscopy and high-frequency ultrasonography, encouraging clinicians to consider pilomatricoma in differential diagnoses of nodular lesions across all ages.
January 2024 in “JCEM case reports” In this clinical case report, a man with Birt Hogg Dube syndrome presented with parathyroid cancer, the first such case according to the authors, highlighting a potential link between Folliculin gene mutations and parathyroid cancer development.
October 2023 in “Research Review” This source describes the development, structure, and types of skin appendage tumors, noting both benign and malignant forms, potential associations with syndromes, and categories based on follicular differentiation.
September 2023 in “Curēus” This source discusses the complexity of cancer research, emphasizing that despite extensive studies, a comprehensive understanding of metastatic progression and therapeutic development remains elusive, and underscores the importance of animal models in breast cancer research.
In this study, a 37-year-old female with resistant hypertension and signs of Cushing's syndrome and primary aldosteronism was found to have normal cortisol levels but high levels of cortisol and aldosterone via adrenal venous sampling, leading to a diagnosis confirmed by right adrenalectomy.
March 2023 in “Zdorov'â čolovìka” This article reviews how various medications, such as antihypertensives, chemotherapy, and hormonal contraceptives, are associated with negative effects on sexual desire and function but reports no new clinical results.
January 2022 in “Autopsy and Case Reports” This article describes a case of pilomatricoma in a 22-year-old male with successful surgical excision and no recurrence, highlighting its histopathological features and typical clinical presentation.
April 2020 in “Journal of the Endocrine Society” This case report highlights Leydig cell hyperplasia as a rare cause of increased testosterone and postmenopausal hirsutism, resolved after bilateral salpingo-oophorectomy in a 64-year-old woman.
January 2016 in “Archivio italiano di urologia, andrologia” This article reviews treatment-induced sexual dysfunctions related to 5-alpha-reductase inhibitors and reports no new results; it highlights the need to better define and understand this controversial topic.
This abstract contains subscription and access information for Wolters Kluwer Health journals but reports no research findings.
March 2010 in “Ejc Supplements” This study highlights a paradox where valproic acid, known for causing hair loss, may also promote hair growth when applied topically.