August 2026 in “JAMA Dermatology” This study found that upadacitinib significantly improved hair regrowth compared to placebo in adults and adolescents with severe alopecia areata, and demonstrated a positive benefit-risk profile.
9 citations
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August 1952 in “The Journal of Clinical Endocrinology & Metabolism” This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.
April 2018 in “Journal of Investigative Dermatology” This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.
September 2026 in “Advanced Materials Technologies” In a mouse model study, researchers developed a methacrylated hyaluronic acid-based hydrogel microneedle patch co-loaded with finasteride and a carbon monoxide-releasing molecule for androgenetic alopecia, which showed better hair regrowth and safety compared to traditional treatments, offering an innovative approach with minimized systemic side effects.
March 2026 in “Indian Dermatology Online Journal” This report details a case study where a 40-year-old woman experienced allergic contact dermatitis and angioedema-like symptoms after using PPD-containing hair dye. Patch testing confirmed a positive reaction to PPD, highlighting the substance's potential to cause both T-cell and IgE-mediated hypersensitivity reactions.
6 citations
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January 2017 in “Dermato-endocrinology” This study found that androsterone glucuronate (ADT-G) was the only androgenic metabolite sensitive to detecting differences between adult women with acne and controls, and its levels decreased with systemic treatment.
August 2026 in “International Journal of Molecular Sciences” This study found that Atractylodes macrocephala Koidz. extract promotes anagen entry and hair regrowth by enhancing dermal papilla cell activity and supporting hair cycle progression in a mouse model.
June 2026 in “Journal of Sulaimani Medical College” This study found that adipose-derived stem cell exosome injections were more effective than minoxidil in improving hair density and diameter in patients with androgenetic alopecia, with high patient satisfaction and manageable side effects.
May 2025 in “Reactions Weekly”
10 citations
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June 2014 in “Experimental Dermatology” The study found that exogenous decorin administration accelerated the anagen phase and delayed the catagen transition, suggesting it may act as a positive regulator of the hair cycle.
December 2025 in “The Journal of Nutritional Biochemistry” This study found that kaempferol may stimulate hair growth in androgenetic alopecia by enhancing dermal papilla cell function and reducing dihydrotestosterone-induced damage, showing comparable efficacy to finasteride in a mouse model.
2 citations
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January 2012 in “Journal of Clinical & Experimental Dermatology Research” This study found that adding fexofenadine to DPCP treatment in non-atopic Alopecia areata patients did not significantly improve hair regrowth, but it did significantly reduce treatment-related discomfort.
28 citations
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March 2010 in “British Journal of Dermatology” This abstract contains only supplementary material information and reports no new research findings.
August 2025 in “Journal of Polymer Science” This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.
33 citations
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December 2008 in “Journal of Dermatology” This study found that 0.75% adenosine lotion significantly improved hair growth and thickness in Japanese women with female pattern hair loss compared to a placebo.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
April 2023 in “Journal of Investigative Dermatology” In this study, a novel AR protein degrader was shown to reverse DHT-induced hair regrowth delay in a mouse model of androgenetic alopecia, with minimal circulation and potential side effects.
October 2012 in “Institutional Repositories DataBase (IRDB)” The researchers reported that treatment with adipose-derived stem cell conditioned medium significantly increased hair count in the study participants, suggesting it is an effective therapy for hair regeneration.
November 2021 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This paper evaluates the therapeutic response of androgenetic alopecia to topical application of specific compounds using digital drug delivery but reports no new clinical results.
June 2026 in “Mendeley Data” This dataset provides supplemental material for a study on long-term particulate matter exposure and androgenetic alopecia risk, including additional exposure data and sensitivity analyses, but reports no new clinical results.
6 citations
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August 2022 in “International journal of molecular sciences” This study demonstrated that α-phellandrene promotes dermal papilla cell proliferation through a cAMP-mediated pathway and upregulates VEGF expression, suggesting its potential use in hair loss prevention.
2 citations
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January 2015 December 2016 in “Chinese Journal of Dermatology” This study found that adenosine can promote the growth of human hair follicles and dermal papilla cell proliferation, possibly through increased angiogenin expression.
7 citations
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April 2020 in “Dermatologic Therapy” In this study, nine male cases of androgenetic alopecia showed marked improvement after receiving systemic dexpanthenol treatment.
9 citations
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September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.
2 citations
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January 2020 in “Evidence-based Complementary and Alternative Medicine” This study found that Hataedock may alleviate atopic dermatitis symptoms in mice by maintaining skin homeostasis and improving skin barrier formation through the endocannabinoid system.
July 2024 in “Journal of Investigative Dermatology” This study suggests that macrophages, especially CD206+ subsets, play a key role in hair growth induced by squaric acid dibutyl ester, a therapy used for alopecia areata.
6 citations
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January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This report details the case of an 11-year-old girl with APECED syndrome carrying a unique homozygous mutation in the AIRE gene, the first of its kind documented.
July 2024 in “Journal of Investigative Dermatology” Allergic contact dermatitis may promote hair growth by activating hair follicle stem cells.
3 citations
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November 2019 in “Journal of Investigative Dermatology” In this study, researchers reported that adenosine stimulated hair shaft elongation in cultured human hair follicles by promoting proliferation and prolonging the anagen phase, suggesting the A2B adenosine receptor in outer root sheath keratinocytes as a promising target for treating hair growth disorders like alopecia.