25 citations
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March 2021 in “Australasian Journal of Dermatology” This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
23 citations
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August 1989 in “American Journal of Veterinary Research” In this study, high selenium diets from different sources caused weight and hair loss in pigs, with additional hoof and coronary band problems particularly in those fed sodium selenate.
21 citations
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January 2018 in “Lasers in Medical Science” This study concluded that 12 sessions of fractionated thulium laser treatment improved hair density and thickness in patients with pattern hair loss, with further benefits from adding a growth factor solution post-treatment.
21 citations
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January 2015 in “Oncology Research and Treatment” This study found that sensor-controlled scalp cooling was effective in preventing hair loss during chemotherapy, particularly in premenopausal patients and those without systemic comorbidities or additional medications.
20 citations
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August 2018 in “Clinics in Dermatology” This study highlights the significant psychological impact of alopecia areata, emphasizing the reciprocal relationship between the disorder and psychiatric issues, and underscores the importance of identifying patients needing additional psychological support, especially women, young individuals, and those with severe alopecia or previous psychiatric history.
19 citations
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June 2020 in “International Journal of Dermatology” In this systematic review, oral minoxidil was found to be a safe and effective treatment for androgenetic alopecia and alopecia areata, with additional benefits for female pattern hair loss and other types of alopecia, although common side effects included hypertrichosis and postural hypotension.
19 citations
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February 2008 in “Archives of Dermatological Research” This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.
18 citations
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August 2024 in “eLife” This study investigated immune dysregulation in individuals with Down syndrome and found that treatment with the JAK inhibitor tofacitinib improved skin conditions like alopecia areata and reduced autoimmune markers without severe side effects. Additional research is necessary to understand its broader impacts.
18 citations
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February 2023 in “Journal of Clinical Medicine” This study reported that neuropathic pain is prevalent in 6.7% of hospitalized COVID-19 patients during the acute phase and 34.3% of long COVID patients, highlighting the need for additional research.
15 citations
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May 2017 in “Journal of Dermatological Treatment” In this study, patients with alopecia areata experienced significant hair regrowth using topical latanoprost, minoxidil, or betamethasone valerate, with the addition of latanoprost enhancing the effectiveness of betamethasone valerate, showcasing these treatments as safe and effective options.
14 citations
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September 1954 in “Textile Research Journal” This study found that hair absorbs significant amounts of NaBr from solution, with absorption increasing linearly with solution concentration and additional effects noted with acidic or basic solutions.
11 citations
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March 2017 in “Journal of Biomedical Semantics” This study expands the Drug Ontology to include therapeutic indications for resistant hypertension, malaria, and opioid abuse research, providing a framework for additional drug use representations beyond their original design.
11 citations
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November 1948 in “Journal of Dairy Science” In this study, riboflavin deficiency symptoms were observed in Guernsey calves fed radiated milk, but adding riboflavin improved growth and health, indicating its essential dietary need for young calves.
10 citations
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August 2024 in “Neuroscience & Biobehavioral Reviews” This review discusses the role of neuro(active)steroids, particularly those in the 5α reductase pathway, in modulating dopamine signaling and their impact on neuropsychiatric disorders characterized by dopamine imbalances, including addiction, schizophrenia, and Parkinson's Disease.
This pilot study found that a novel regimen including NuH Hair led to significant hair growth in male patients with androgenic alopecia, regardless of atopy status, with quicker results when additional treatment components were used.
8 citations
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November 2009 in “The Neurologist/The neurologist” This case report highlights a 21-year-old woman with seizures, mental retardation, spastic diplegia, and ichthyosis consistent with Sjogren-Larsson syndrome, and emphasizes the importance of differential diagnosis when additional symptoms are present.
8 citations
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March 2008 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” This case study found that in a male-to-female transgender individual, long-term cyproterone use led to decreased bone mass, which improved with additional oestradiol treatment, highlighting the anabolic role of oestrogens on bone health.
7 citations
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January 2025 in “Journal of Experimental & Clinical Cancer Research” This study found that PRMT5 inhibitors showed potent anti-tumor activity in models of adenoid cystic carcinoma and that combining these inhibitors with lenvatinib may have additional growth-inhibitory effects.
7 citations
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March 2024 in “Veterinary Medicine and Science” In this study, eight dogs with naturally occurring skin wounds were treated with autologous platelet-rich fibrin therapy, which significantly promoted wound healing and tissue regeneration without using additional medications, leading to promising outcomes and minimal scarring.
7 citations
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August 2023 in “Journal of the American Academy of Dermatology” This source reports that the approval of baricitinib and ritlecitinib, which are JAK inhibitors, has marked a significant advancement in treating severe alopecia areata (AA), and suggests that additional treatments with new mechanisms may further improve patient outcomes in the future.
7 citations
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January 2021 in “The Journal of Sexual Medicine” This study demonstrated that testosterone treatment increases muscle strength and alters body composition in transmen, and the addition of dutasteride does not impair these anabolic effects.
7 citations
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May 2017 in “Behavioural brain research” This study found that manipulating neuroactive steroids during early development stages in male rats influences alcohol-induced locomotor sensitivity, suggesting their role in addiction vulnerability.
7 citations
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October 2009 in “Journal of the American Geriatrics Society” This study found that finasteride may reduce inappropriate sexual behaviors in geriatric patients with vascular dementia and benign prostate hyperplasia without serious side effects, though some patients required additional medications.
6 citations
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June 2024 in “Gels” In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.
6 citations
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February 2023 in “International Journal of Women’s Dermatology” This study found that insurance coverage for cranial hair prostheses in patients with alopecia areata is generally inadequate, adding to their financial and psychological burdens.
6 citations
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November 2020 in “Molecular and Cellular Endocrinology” This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.
6 citations
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August 2017 in “Physiological Research” This study suggests that setipiprant's inhibitory effect on aldose reductase may contribute to its anti-inflammatory properties, adding a possible mechanism beyond its known action on the prostaglandin D2 receptor.
6 citations
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March 2009 in “Pigment Cell & Melanoma Research” This study suggests that a purified sphingolipid fraction can activate melanocyte stem cells via p38 signalling, potentially offering a non-UV-based treatment for vitiligo, though additional validation is needed.
5 citations
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November 2022 in “Journal of Ginseng Research/Journal of ginseng research” This study investigated the role of autophagy in human dermal papilla cells and found that inhibiting autophagy accelerates the catagen phase by reducing Wnt/β-catenin signaling. Furthermore, adding ginsenoside Re appears to restore autophagy, suggesting potential benefits for mitigating hair loss linked to autophagy inhibition.
5 citations
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June 2022 in “Frontiers in immunology” This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.