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5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.

This study found that the androgen precursors DHEA and androstenedione stimulated androgen-sensitive parameters in the sebaceous glands of the skin in castrated male hamsters.

This review discusses hormonal manipulation for conditions like prostatic disorders and skin issues and highlights promising treatments like casodex and finasteride, but it reports no new clinical results.

This study discusses various anti-cancer therapies, including chemotherapy and immunotherapy, emphasizing the challenges in classifying these medications due to their diverse chemical compositions, mechanisms of action, and effectiveness against different types of cancer.

Adrenocortical extract is less effective at stopping hair growth in young rats than in adult rats.

This case report suggests that long-acting injectable risperidone may induce hirsutism in some patients, and clinicians should monitor for this potential side effect when prescribing this antipsychotic.

Haloperidol decanoate can cause alopecia areata.

This study found that topical simvastatin induced remission and hair regrowth in a mouse model of alopecia areata, potentially by modulating T cell activity and reducing pro-inflammatory cytokine signaling.

This study highlights that silver nanoparticles can enhance the regeneration of hair follicles and improve healing in surgically wounded rabbit skin and injured rat muscles.

Oral contraceptives can help treat skin issues like acne and excess hair.

This review explores current concepts of steroid action in skin health and healing but provides no new clinical findings.

In this narrative review, researchers found that biomimetic peptides, which mimic natural biological functions, show potential in improving hair density and thickness in people with alopecia, although more robust clinical studies are needed to confirm their efficacy for clinical use.

In this study, researchers developed and evaluated a herbal dual-action anti-dandruff shampoo, which demonstrated effective dandruff control, improved scalp health, and minimal irritation, making it a potentially safe and economical alternative to synthetic formulations for regular hair care.

This study evaluated a newly formulated herbal anti-dandruff shampoo containing natural ingredients such as neem and aloe vera, finding it effective and safe for dandruff control, with good cleansing, conditioning, and minimal irritation.

In this study, a new herbal hair serum using a dual-phase system effectively reduced scalp flakiness and hair fall in a six-week trial, combining oil-based growth stimulants and water-based antimicrobial agents for comprehensive scalp and hair health.

This study evaluated a novel Dual-Phase Herbal Elixir aimed at managing hair fall and dandruff, finding that its unique oil and aqueous layers significantly reduced scalp flakiness and hair fall in a six-week trial, underscoring its potential as a natural hair care alternative.

This source suggests that alitretinoin may be a safe and potentially effective treatment for patients with mild to moderate alopecia areata not responding to conventional therapies, though further research is needed to confirm its role, either alone or as an adjunct.

In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.

This study reviewed literature on signaling pathways and concluded that these pathways are crucial pharmacological targets, influencing the mechanisms of drugs used in neurological, cardiovascular, and oncological treatments to correct signal transmission disturbances.

Secukinumab reduces immune activity in hidradenitis suppurativa skin.

This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.

Photobiomodulation effectively stimulates hair growth and reduces hair loss.

This literature review reports that micro-needle radiofrequency is increasingly recognized in aesthetic medicine as a safe, effective treatment for various skin conditions, but further research is needed to optimize treatment parameters for the best outcomes.

This review concluded that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage and promoting cancer development and metastasis from stem cell origins.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage that promotes cancer development and metastasis, by affecting normal stem cells, cancer stem cells, and cancer cells.

This review highlights that chronic inflammation leads to ongoing activation of stem cells, causing DNA damage accumulation, which can promote cancer development and metastasis.

In this review, researchers concluded that chronic inflammation perpetually activates stem cells, allowing DNA damage accumulation and potentially promoting cancer development and metastasis by converting stem cells into cancer cells.

This literature review reports that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage, and eventually promoting cancer development and metastasis even before stem cells become cancerous.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, which may accumulate DNA damage and ultimately promote cancer, while also facilitating cancer metastasis.