43 citations
,
May 1988 in “British Journal of Dermatology” Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
30 citations
,
January 2018 in “Clinics in Dermatology” Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.
6 citations
,
January 2018 in “Dermato-endocrinology” Darkened knuckles can be an early sign of insulin resistance.
February 2022 in “International journal of reproduction, contraception, obstetrics and gynecology” Acanthosis nigricans in teenage girls with PCOS is a sign of obesity, not insulin resistance or glucose intolerance.
January 2017 in “Journal of clinical & experimental dermatology research” The case shows skin changes can indicate deeper health issues like insulin resistance, which are challenging to manage.
January 1988 The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
9 citations
,
October 2014 in “Experimental and Clinical Endocrinology & Diabetes” Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.
23 citations
,
March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
7 citations
,
January 2015 in “Case reports in endocrinology” The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
January 2015 in “International Journal of Research in Medical Sciences” A patient with HAIR-AN syndrome, PCOS, and Hashimoto's thyroiditis improved with early diagnosis and treatment to prevent serious health problems.
6 citations
,
February 2014 in “Human & experimental toxicology” Testosterone injections can cause skin darkening and thickening.
1 citations
,
January 1996 in “Gynecological endocrinology” Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
3 citations
,
February 2002 in “The American journal of psychiatry” Stopping birth control pills may have triggered a manic episode in a woman with HAIR-AN syndrome.
2 citations
,
January 2018 in “Sovremennye problemy nauki i obrazovaniâ” Hirsutism and acanthosis nigricans are important for diagnosing PCOS; dermatologists play a key role in early detection and treatment.
May 2016 in “Journal of The American Academy of Dermatology” Hirsutism and acanthosis nigricans are reliable skin signs of PCOS and suggest the need for further tests for related health issues.
May 2016 in “Journal of The American Academy of Dermatology” Hirsutism and acanthosis nigricans are reliable skin signs of PCOS linked to metabolic issues, while acne is not a reliable marker of the condition.
6 citations
,
March 2014 in “Actas Dermo-Sifiliográficas” Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.
March 2020 in “International journal of contemporary medical research” Patients with metabolic syndrome often have skin problems like acanthosis nigricans and skin tags, and early treatment is important to prevent serious issues.
405 citations
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June 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.
September 2019 in “Journal of evolution of medical and dental sciences” Obesity significantly affects skin health, causing conditions like acanthosis nigricans and skin tags, and should be considered during skin exams.
7 citations
,
February 2011 in “Journal of The American Academy of Dermatology” Most women with hyperandrogenism first show acne, and skin conditions like hirsutism and acanthosis nigricans are good indicators of the condition.
January 2014 in “John Wiley & Sons, Ltd eBooks” Skin symptoms can indicate endocrine disorders and have various treatments.
6 citations
,
September 2015 in “Clinics in Dermatology” Acne and other skin conditions can indicate internal diseases like Polycystic Ovary Syndrome (PCOS), and early treatment can prevent long-term issues.
December 2023 in “PubMed” Metformin and liraglutide improved symptoms of HAIR-AN syndrome in a child.
3 citations
,
January 2010 in “Elsevier eBooks” The document describes various skin conditions, their features, and treatments but lacks detailed study size information.
947 citations
,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
76 citations
,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
71 citations
,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
50 citations
,
January 2013 in “Indian Journal of Dermatology” Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.
27 citations
,
December 2016 in “Dermatology and Therapy” Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.