July 2023 in “Journal of ayurveda and integrated medical sciences” This case report details the treatment of a 28-year-old woman with PCOS symptoms, including irregular menstruation, weight gain, and hair loss, using Ayurvedic management after ultrasound showed a bilateral PCO pattern.
15 citations
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January 2010 in “Reproduction, Fertility and Development” This study found that Han Chinese women carrying the rs6152A allele had a significantly higher risk of developing polycystic ovary syndrome compared to those with the rs6152GG genotype.
June 2025 in “Current Issues in Molecular Biology” In this laboratory study, Cucumis melo var. makuwa leaf extract significantly reduced DHT-induced apoptosis in human dermal papilla cells by modulating androgen receptor activity and gene expression, suggesting potential as a therapy for androgenetic alopecia.
21 citations
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March 2019 in “Critical Reviews in Clinical Laboratory Sciences” This review discusses the role of the androgen receptor in breast cancer diagnosis and treatment, and notes a lack of new research results on its therapeutic potential.
May 2025 in “International Ayurvedic Medical Journal” This review discusses meditation and Suryanamaskar for women with PCOS and reports no new clinical results; the authors emphasize Suryanamaskar's potential benefits and the need for lifestyle modifications.
10 citations
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January 2010 in “Acta Histochemica Et Cytochemica” This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.
February 2024 in “Journal of ayurveda and integrated medical sciences” This case study suggests that Ayurvedic treatment, including Karanj oil, herbal churna, and leech therapy, provided significant hair regrowth in a 16-year-old with alopecia areata after three months, despite previous unsuccessful conventional medicine treatments.
February 2024 in “Journal of ayurveda and integrated medical sciences” This paper reviews Ayurvedic concepts related to PCOS and compares them with PCOS symptoms, without presenting new clinical findings.
January 2022 in “International Research Journal of Ayurveda & Yoga” This narrative review explores Ayurvedic concepts related to polycystic ovarian syndrome and reports no new clinical results; the authors suggest traditional treatment approaches involving lifestyle and specific therapies.
October 2019 in “International Journal of AYUSH Case Reports” This case study reported that a 29-year-old male patient with alopecia areata patchy experienced hair regrowth and relief from scalp itching and dandruff after using medicinal leech therapy and specific internal medicines for three months.
23 citations
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January 2014 in “International Journal of Biological Sciences” This study found that African American men with prostate cancer have higher rates of somatic and germline androgen receptor mutations than Caucasian American men, which may contribute to ethnic differences in disease progression and outcomes.
4 citations
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May 2014 in “PubMed” This study found that monoethanolamine-based hair color formulations caused significantly more damage to hair than ammonia-based formulations, especially at high concentrations.
June 2024 in “Research Square (Research Square)” This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.
November 2015 in “Clin-Alert” Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
3 citations
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February 1996 in “Dermatologic Surgery” This article argues against the widespread use of isolated frontal forelock hair transplantation for most patients, suggesting more extensive coverage is often a reasonable option.
506 citations
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January 2012 in “Molecular and Cellular Endocrinology” This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
July 2021 in “Advances in laboratory medicine” This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.
2295 citations
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August 2012 in “The international journal of transgenderism/International journal of transgenderism” This publication reviews the World Professional Association for Transgender Health's Standards of Care for supporting transgender and gender nonconforming people, with adjustments needed for diverse global contexts and no new clinical results.
303 citations
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August 1971 in “The American Journal of Medicine” This report suggests that in vitiligo, melanocytes may be destroyed by the same factors necessary for melanin production, contributing to the skin's depigmentation.
245 citations
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January 2010 in “Blood” This study suggests that antihepcidin antibodies may effectively treat inflammatory anemia by manipulating iron metabolism, based on experiments conducted in mouse models and hHepc knock-in mice.
160 citations
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January 2017 in “Development” This study found that hypertrophic chondrocytes at the fracture callus border may convert to osteoblasts, influenced by vasculature and pluripotency gene expression.
131 citations
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May 2015 in “Experimental Dermatology” This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.
88 citations
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August 2019 in “Nature communications” In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.
81 citations
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February 2014 in “EMBO molecular medicine” This study found that prolonged Nrf2 activation in mouse keratinocytes led to enlarged sebaceous glands, hair loss, and cysts, suggesting a role for Nrf2 in conditions like MADISH.
72 citations
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November 2015 in “Multiple Sclerosis and Related Disorders” This study concluded that teriflunomide has a consistent and manageable safety profile, with common mild-to-moderate adverse events and no new safety concerns identified over up to 12 years of treatment.
58 citations
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September 2019 in “EMBO Molecular Medicine” This study found that the CDK4/6 inhibitor palbociclib may protect human hair follicles from the damaging effects of taxane chemotherapy by inducing G1 arrest in stem/progenitor cells.
58 citations
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November 2012 in “PLoS ONE” This study found that dermal fibroblast cultures, especially those with higher alpha-smooth muscle actin expression, can be used to produce skin-derived precursor cells, unlike human hair follicle dermal papilla cultures.
48 citations
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January 2017 in “International Journal of Trichology” This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.
39 citations
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September 2015 in “Clinical Therapeutics” This review summarizes updated US prescribing information for teriflunomide in relapsing multiple sclerosis, highlighting its efficacy in reducing lesion activity and relapse rates but noting potential adverse effects such as headache and diarrhea.
36 citations
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August 2016 in “The Plant cell” This study found that downregulating PI3K in common bean severely impaired symbiosis with beneficial microorganisms, indicating an essential role for autophagy-related processes in these mutualistic interactions.