106 citations,
April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
The mutation helps mice handle heat better without affecting hair growth.
30 citations,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
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January 2008 in “US endocrinology” Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
1 citations,
January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
July 2022 in “Research Square (Research Square)” Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.
[object Object] 51 citations,
September 2008 in “Journal of Investigative Dermatology” Vitamin D receptor may help protect against UV-induced skin cancer.
6 citations,
April 2018 in “Obstetrics, gynaecology and reproductive medicine” Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
55 citations,
November 2010 in “Journal of Allergy and Clinical Immunology” The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.
March 2021 in “Bioscientia medicina” Androgen affects oil production and hair growth in the skin.
24 citations,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
73 citations,
April 1999 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Vitamin D receptor is crucial for bone health and mineral metabolism.
4 citations,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” EGFR inhibitors cause skin issues and hair loss by weakening skin defenses, suggesting antibiotics and targeted treatments can help.
March 2008 in “British Journal of Pharmacology” Enzymes play crucial roles in metabolism, health, and disease management.
October 2024 in “Journal of the Endocrine Society” A woman experienced fluctuating thyroid conditions and eye disease, but her symptoms improved with treatment.
June 2018 in “Biomedical Journal of Scientific and Technical Research” Men with lower 2nd to 4th finger ratios tend to have larger sinus volumes.
10 citations,
December 2021 in “Frontiers in cell and developmental biology” Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
January 2023 in “Karger Kompass. Dermatologie” Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
5 citations,
May 2021 in “Small ruminant research” The study found specific proteins that could mark different growth stages of cashmere goat hair and may help improve cashmere production.
2 citations,
February 2003 in “Annals of Neurology” Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
14 citations,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
9 citations,
September 2015 in “Reproductive Biomedicine Online” Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.
January 2014 in “Revista Brasileira de Cirurgia Plástica” A new method using gentian violet and a protective spray can improve symmetry and reduce surgery time in hair restoration, but it's only effective for total hair loss, not diffuse hair loss or follow-up treatments.
55 citations,
January 2007 in “Climacteric” Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
19 citations,
November 2010 in “PubMed” New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.
227 citations,
January 1998 in “Journal of biological chemistry/The Journal of biological chemistry” Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
39 citations,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
June 2019 in “International journal of dermatology and venereology” A man developed skin issues from cancer medication, which improved with specific treatments.
15 citations,
January 2009 in “International Journal of Andrology” Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.