25 citations
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October 2022 in “Ophthalmic Research” In this study, 650 nm low-level red light therapy may cause a short-term transient increase in retinal fovea perfusion density in children, with no lasting effects observed at 1 hour post-treatment.
The 1540nm fractional erbium-glass laser helps treat hair loss caused by hormones.
September 2024 in “Archives of Dermatological Research” This study found that both red and green LED therapies combined with a microneedling patch significantly improved hair density and diameter in androgenetic alopecia patients over 24 weeks, with no serious side effects and similar efficacy between the two light wavelengths.
September 2017 in “Journal of Investigative Dermatology” In this study, low-dose 453 nm blue light appeared to enhance hair growth by interacting with specific photoreceptors in the outer root sheath cells.
5 citations
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September 2019 in “Journal of Biomedical Optics” This study determined in-vivo skin damage thresholds for 1319-nm laser exposure in pigs, and the findings may enhance understanding of thermal damage mechanisms and inform laser safety standards.
63 citations
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January 2006 in “Journal of cosmetic and laser therapy” This study found that pulsed infrared diode laser therapy (904 nm) was effective in promoting hair regrowth in 94% of patients with resistant patches of alopecia areata.
59 citations
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September 2011 in “Lasers in Medical Science” This study concluded that the 800-nm diode laser is effective in enhancing skin structure and collagen expression via the TGF-β/Smad pathway, suggesting potential for non-ablative rejuvenation.
April 2025 in “Asian Journal of Surgery” 23 citations
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July 2021 in “Life” This review evaluates the potential benefits and mechanisms of blue light therapy for skin conditions like atopic dermatitis and acne, but highlights the need for further research on safety and clinical protocols.
22 citations
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September 2022 in “Medicina” This study found that the dual-wavelength non-ablative fractional laser provides enhanced skin rejuvenation by increasing thermal lesion coverage and collagen remodeling compared to using the CO2 laser alone in an ex vivo setting.
108 citations
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December 2003 in “Lasers in surgery and medicine” This study found that combining near-infrared laser phototherapy with indocyanine green application may improve acne vulgaris by reducing active lesions and inflammation without side effects.
2 citations
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July 2004 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that multiple treatments combining NIR laser phototherapy with ICG significantly reduced inflammation and improved skin condition in acne without side effects.
This study observed increased proliferation and certain gene expressions in dermal papilla cells exposed to an 808 nm laser diode array at doses above 0.5 J/cm².
1 citations
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June 2024 in “JMIR Dermatology” This study found that 675 nm laser treatment improved androgenetic alopecia in Indian patients, resulting in significant increases in hair count, density, and thickness after 14 sessions, enhancing the anagen phase and other hair-related parameters.
47 citations
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August 2011 in “Journal of The European Academy of Dermatology and Venereology” This study found that treatment with a 1550 nm fractional erbium–glass laser increased hair density and thickness in women with female pattern hair loss, suggesting it may be an effective and safe option.
6 citations
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September 2018 in “Journal of Dermatological Treatment” This review examines the FDA's 510(k) approval process for low-level laser therapy devices used in treating androgenetic alopecia and reports no new clinical findings.
26 citations
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April 1999 in “Dermatologic Clinics” This article reviews the basics of hair follicle biology, laser/tissue interactions, and hirsutism and hypertrichosis causes, discussing the long-pulsed alexandrite laser's role in hair reduction without reporting new clinical results.
May 2022 in “Голова и шея.” In this pilot study, researchers observed that low-intensity laser radiation at 445±40 nm increased the temperature of gingival tissues in Wistar rats by 8.37°C without exceeding the safety threshold, suggesting potential for clinical trials.
February 2009 in “Journal of The American Academy of Dermatology” Fractional infrared technology is effective and safe for treating cervical laxity.
December 2022 in “IntechOpen eBooks” This source evaluates the clinical effectiveness of 308 nm monochromatic excimer phototherapy in treating moderate-to-severe alopecia areata, noting that both laser and lamp methods show promise without significant risks.
23 citations
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April 1999 in “Dermatologic Clinics” This study found that the Epilight multiple wavelength pulsed-intense light source was effective for long-lasting hair removal, particularly in individuals with dark hair and light skin.
January 2026 in “Nature Communications” This study presented a new wearable textile-based device with near-infrared OLEDs that significantly reduced cell aging markers and improved cell migration in vitro, suggesting it as a promising, non-invasive phototherapy option for hair follicle treatment and hair-loss management.
October 2024 in “Photodermatology Photoimmunology & Photomedicine” In this study, participants with androgenetic alopecia who used an LED helmet emitting red and green light experienced significant improvements in hair growth measures, with red light showing superior results in increasing hair diameter and reducing vellus hair density over 6 months.
September 2025 in “Acta Medica International” In this study, a triple wavelength laser was found to be highly effective and well-tolerated for reducing hair in Indian women with Fitzpatrick skin types III and IV, achieving an average hair count reduction of 86.5%, with only mild and transient adverse effects observed.
September 2024 in “Journal of the Pakistan Medical Association” In this experimental study, laser irradiation significantly altered the gene expression of cytokines in cultured human T-cell lymphocytes, suggesting that such laser light may photobiomodulate cytokine production in vitro.
May 2017 in “Journal of The American Academy of Dermatology” 595 nm pulsed dye laser is a cost-effective treatment for nonmelanoma skin cancer with a low recurrence rate.
117 citations
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September 2013 in “Lasers in Surgery and Medicine” This study found that low level laser therapy at 655 nm significantly increased hair counts in males with androgenetic alopecia.
1 citations
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November 2016 in “Experimental and Therapeutic Medicine” In this study using guinea pigs, the low-dose 800 nm semiconductor laser was found to effectively treat skin blackheads and coarse pores by promoting hair follicle cell apoptosis, while maintaining PCNA expression levels in sebaceous glands.
This article reviews low-level light therapy for various types of hair loss and reports no new clinical results; the authors note its safety and advantages but lack data on individual treatment response.
January 2000 in “Optics Letters” This study found that the maximum infrared temperature of laser-irradiated hair depends on melanin type, with eumelanin-rich hair reaching higher temperatures than pheomelanin-containing hair.