24 citations
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March 2015 in “Dermatologic Surgery” This review discusses the modest efficacy of home-use laser and light devices for conditions like hair removal and acne, noting limited evidence and a lack of robust trials.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
11 citations
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February 2020 in “Dermatology and therapy” This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
8 citations
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October 2020 in “Lasers in Medical Science” This review suggests that low-level light therapy can promote hair growth in patients with androgenetic alopecia, but more research is needed to standardize treatment parameters and assess long-term safety and efficacy.
4 citations
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February 2014 in “Proceedings of SPIE” This review discusses the diverse applications of low-level laser therapy in aesthetic dermatology, especially for managing alopecia, but notes that comprehensive literature on its effectiveness is lacking.
64 citations
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June 2020 in “PLoS ONE” This study found that red light exposure significantly enhanced the growth, phytochemical content, and therapeutic potential of Eclipta alba callus cultures compared to other multispectral light exposures.
8 citations
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July 2020 in “Medicine” In this study, low-level light therapy using a new helmet-type device significantly increased hair density and thickness in patients with androgenetic alopecia, showing no adverse events or side effects, suggesting it may be a safe and effective treatment option for both sexes.
6 citations
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June 2013 in “British Journal of Dermatology” This study found that intense pulsed light treatment primarily targets pigmented structures in hair follicles and may damage dermal papilla cells at high energy levels, but stem cells are mostly spared.
38 citations
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January 2023 in “International Journal of Medical Sciences” This review discusses the potential of repeated low-level red-light therapy to inhibit myopia progression through metabolic effects, highlighting its molecular and cellular impact, but reports no new clinical results.
19 citations
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September 2011 in “Seminars in Cutaneous Medicine and Surgery” This review discusses home-use laser and light skin devices for various dermatological purposes and reports no new clinical findings; the authors highlight the need for dermatologists to evaluate these devices' clinical value.
June 2026 in “Ophthalmology and Therapy” This review concluded that near-infrared and red light photobiomodulation shows potential for certain ocular conditions like age-related macular degeneration and dry eye disease, but clinical evidence is still mixed and insufficient to establish it as a standard therapy.
165 citations
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August 2013 in “Lasers in Surgery and Medicine” This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
60 citations
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November 2020 in “International Journal of Medical Sciences” This review highlights the potential of near-infrared light therapy to improve metabolic, antioxidant, and cognitive functions without adverse effects, and supports its use for visual and neurological conditions through molecular and cellular mechanisms, as reported in this source.
December 2025 in “Aesthetic Plastic Surgery” This study reported that the new near-infrared LED device showed significant improvements in skin rejuvenation and a slight increase in hair growth, with further research recommended for broader validation.
April 2021 in “JOJ dermatology & cosmetics” This study found that a combination treatment of laser photobiomodulation and plasma jet therapy was effective in improving alopecia areata in a 38-year-old woman after 14 sessions over three months, as evidenced by comparative photo documentation.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
May 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
December 2024 in “Dermatologic Surgery” This study observed that pooled analysis of LED caps increased hair density in patients with androgenetic alopecia compared to sham, achieving 28.5 more hairs per cm².
520 citations
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January 2017 in “AIMS biophysics” This review discusses the effects of photobiomodulation, particularly its potential to reduce inflammation in various conditions, but it does not report new clinical findings.
25 citations
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February 2023 in “Aesthetic Surgery Journal” This review concludes that current clinical and preclinical evidence does not indicate oncologic safety concerns linked to photobiomodulation therapy for skin rejuvenation, including no clear evidence of increased cancer risk.
10 citations
,
September 2022 in “Journal of Biophotonics” This study analyzed clinical and histological reports and concluded that blue light therapy is safe for human skin, with potential photoprotective effects against UV irradiation due to its impact on skin pigmentation mediated by Opsin-3.
9 citations
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January 2018 in “Medical research archives” This review discusses the therapeutic use of photobiomodulation for various skin conditions, highlighting its efficacy in accelerating tissue repair, reducing inflammation, and treating pigmentary disorders and other skin diseases, but it reports no new clinical results.
August 2025 in “Photodermatology Photoimmunology & Photomedicine” This review found that LED therapy, using light in specific wavelengths, may offer effective, non-invasive treatment options for various skin conditions, including acne, melasma, photoaging, and wound healing.
February 2025 in “Cosmetics” This narrative review explored how blue light therapy may offer therapeutic benefits for various skin disorders by affecting microbial activity and immune responses, promoting hair growth, and aiding skin rejuvenation and healing.
January 2023 in “Dermatologic Therapy” This study evaluated a novel hand-held low-level light therapy device for treating mild-to-moderate acne, finding it significantly reduced inflammatory lesions and moderate acne severity without severe adverse reactions, while also reducing Cutibacterium acnes viability in vitro.
4 citations
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December 2021 in “Applied sciences” This study observed that a combination of micro-needling and low-level light/laser therapy significantly increased hair density in patients with mild to moderate androgenic alopecia, showing an increase of 12 hairs/cm² after 16 weeks, compared to baseline.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, periodic exposure to red light in aged mice led to increased histone acetylation and activated mitochondrial fatty acid oxidation, which collectively mitigated cellular aging by modulating metabolism, inflammation, and gene expression.
This review of existing literature reports that photobiomodulation shows high effectiveness and safety in treating dermatological conditions like acne, psoriasis, and alopecia, though standardized clinical trials are needed to further validate its therapeutic benefits.
January 2026 in “Nature Communications” This study presented a new wearable textile-based device with near-infrared OLEDs that significantly reduced cell aging markers and improved cell migration in vitro, suggesting it as a promising, non-invasive phototherapy option for hair follicle treatment and hair-loss management.
2 citations
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January 2022 in “BioMed Research International” This study found that using an LED array with an 863 nm wavelength delayed tumor development and reduced systemic inflammatory cytokines in DMBA/TPA-induced mouse skin tumors, suggesting potential but limited benefits of light therapy.