research 5-Alpha-Reductase Inhibitor Treatment for Frontal Fibrosing Alopecia: A Myth or Truth?
5-Alpha-Reductase inhibitors might help slow down hair loss in Frontal Fibrosing Alopecia but are not a primary treatment and need more research.
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180-210 / 271 results research Improvement of Androgenetic Alopecia with Combined Low-Dose Dutasteride and Finasteride Therapy: A Case Report
Combining low-dose dutasteride with finasteride improved a man's hair loss.
research Combined Treatment of Benign Prostatic Syndrome with Tamsulosin and Finasteride: Literature Review and Prescription Data
Using tamsulosin and finasteride together for benign prostatic syndrome has increased and shows improvement in symptoms, but more reliable comparisons are needed.
research Androgenetic Alopecia: New Insights Into the Pathogenesis and Mechanism of Hair Loss
New model shows muscle affects hair loss differently in men and women.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole
Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.
research The Effect of Administration and Discontinuation of Finasteride in Male Rats
Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.
research Discovery and Clinical Development of Dutasteride, a Potent Dual 5α-Reductase Inhibitor
Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.
research Current and Future Medical Treatment of Androgenetic Alopecia
Treatments for hair loss vary, but cell-based options may be the future.
research Synthesis of Phenanthridin-3-One Derivatives: Non-Steroidal Inhibitors of Steroid 5-Alpha-Reductase
New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
research Improvement of General Symptoms in a Chronic Psychotic Patient Treated with Finasteride: Case Report
Finasteride improved symptoms in a schizophrenia patient.
research Management of Androgenetic Alopecia in Men: Established Options and Emerging Therapies
New treatments for male pattern hair loss look promising, but established treatments are still the main option.
research Allopregnanolone Promotes Proliferation and Differential Gene Expression in Human Glioblastoma Cells
Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
research Pharmacokinetic Parameters and Mechanisms of Inhibition of Rat Type 1 and 2 Steroid 5α-Reductases: Determinants for Different In Vivo Activities of GI198745 and Finasteride in the Rat
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Dutasteride more effectively treats hair loss than finasteride, but may increase risk of altered libido.
research Antioxidant and 5α-Reductase Inhibitory Activity of Momordica Charantia Extract, and Development and Characterization of Microemulsion
Bitter melon extract may help prevent hair loss and can be used in cosmetic products.
research Potential Remedial Effects of Solanum Nigrum Berries on Alopecia: An In Vivo Study
Solanum nigrum extract may help regrow hair.
research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
research FCE 28260, A New 5α-Reductase Inhibitor: In Vitro and In Vivo Effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Androgenic Alopecia May Have Evolved to Protect Men from Prostate Cancer by Increasing Skin Exposure to Ultraviolet Radiation
Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research 3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1
A new compound effectively inhibits human 5α-reductase 1.
research Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia
A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research Analytical Methods of Dutasteride: An Overview
Dutasteride is more effective than finasteride for hair loss treatment.
research An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects
Herbal formula shows promise for hair loss treatment.