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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Hair loss can be treated with medications like minoxidil and finasteride or surgery, but treatment effectiveness varies by alopecia type and accurate diagnosis is important.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Androgens can both increase body hair and cause scalp hair loss.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.