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Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

New tests detect finasteride and dutasteride in urine quickly and easily.

Testosterone's muscle-building effects do not require its conversion to DHT.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Finasteride affects prostate weights and pituitary activity differently with age.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Finasteride helps protect brain in old male rats.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.