110 citations,
January 2014 in “The Journal of Sexual Medicine” Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
76 citations,
January 2010 in “Clinics in Dermatology” Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
65 citations,
January 2011 in “Frontiers in Endocrinology” Neurosteroids show promise for treating epilepsy and more research is needed.
61 citations,
February 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
58 citations,
January 2013 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
54 citations,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
53 citations,
May 1986 in “Clinics in endocrinology and metabolism” Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
52 citations,
February 2014 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
50 citations,
April 2000 in “Fertility and Sterility” Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
48 citations,
July 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
37 citations,
April 2014 in “Journal of Dermatology” Valproic acid increases hair count in men with hair loss.
37 citations,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
34 citations,
July 2020 in “Frontiers in immunology” Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
33 citations,
October 2004 in “Archives of Dermatological Research” Large prostate links to more hair loss, but age of onset doesn't affect it.
33 citations,
November 2018 in “Facial Plastic Surgery Clinics of North America” The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
32 citations,
February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
32 citations,
September 2016 in “Journal of Dermatology” Dutasteride safely promotes hair growth and reduces hair loss, with mild side effects.
30 citations,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
27 citations,
August 1999 in “Urology” Finasteride improves urinary function in men for 2 years.
26 citations,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
23 citations,
January 1998 in “Urological research” Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
20 citations,
November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
19 citations,
October 2016 in “Pharmacotherapy” Finasteride for hair loss increases risk of long-lasting sexual dysfunction.
17 citations,
January 2013 in “Our Dermatology Online” Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.
15 citations,
March 2014 in “Molecular Medicine Reports” α-spinasterol from Melandrium firmum can help reduce prostate enlargement.
14 citations,
March 2017 in “Sexual Medicine” Finasteride side effects in young men may be linked to specific gene variations.
14 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Some nonsurgical hair loss treatments are effective, especially if started early.
13 citations,
October 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
11 citations,
January 2022 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.