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The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Finasteride may affect PNMT, causing side effects.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Finasteride causes harmful organ changes in female mice.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Advancements in hair biology include new treatments and tools for hair growth and alopecia.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Testosterone therapy increases bone density in older men with low testosterone levels.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Androgens can both increase and decrease hair growth in different parts of the body.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Zinc is effective for treating various skin conditions, including warts and acne.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride may cause long-lasting sexual side effects.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.