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Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Testosterone therapy increases bone density in older men with low testosterone levels.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Niosomes improve minoxidil skin delivery for hair loss treatment.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Fungi-produced compounds can change plant root growth.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Fullerenes show potential in skin care but need more safety research.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.