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Rats had lasting erectile problems after stopping a certain medication.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

A new compound effectively inhibits human 5α-reductase 1.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Compound 15a was effective in inhibiting 5α-reductase.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

The herbal hair gel could be a safe hair growth treatment with minimal side effects.

Finasteride may affect PNMT, causing side effects.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Babies were mostly born healthy from fathers who took finasteride, but some pregnancies ended early; more research is needed.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Higher dihydrotestosterone may be linked to more inflammation in COVID-19 patients with low testosterone.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Four-amino acid part makes enzyme sensitive to finasteride.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.