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Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Finasteride may affect PNMT, causing side effects.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Eclipta alba extract could be a promising natural treatment for hair loss.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Glioblastoma cells can make androgens, which might help the tumor grow.

New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Solanum nigrum may help treat hair loss.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

The study created a new method to test drugs that affect hormone processing in skin.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.