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Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

COVID-19 can cause various skin issues, like rashes and lesions, which are more common in younger patients and can be linked to more severe complications.

Red pigmented rice, like Sang-Yod rice, could help promote hair growth and prevent hair loss.

12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

Male hormones can cause hair loss, but treatments like Minoxidil and Finasteride can help, and targeting TGF-B1 could be a future solution.

The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.

Male pattern hair loss may be linked to the developmental origins of hair follicles.

Finasteride negatively affects fish reproduction and gonadal development.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.