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Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Finasteride may increase suicide risk; more research needed.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Hair and nails can show hormone changes during puberty in dogs.

Muscles can make their own androgens, which may help muscle growth.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Too much androgen can cause hair loss; finasteride may help.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.