1 citations
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November 2024 in “IP Indian Journal of Clinical and Experimental Dermatology” This study in Pudukottai district found that among 5870 individuals attending rural health camps, 1468 had skin complaints, with non-infectious conditions like eczema being most common, followed by fungal, bacterial, and arthropod infections.
This study presents a new model for the progression of androgenetic alopecia, suggesting that the loss of attachment between the bulge's stem cells and the arrector pili muscle may contribute to irreversible hair miniaturization.
December 2015 in “Dermatologic Surgery” Double trichophytic closure effectively repairs thin scalp scars, reducing financial burden.
159 citations
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July 2014 in “Molecular pharmaceutics” This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.
62 citations
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January 2000 in “Developmental dynamics” This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.
37 citations
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January 2022 in “Frontiers in Genetics” This study found that dermal sheath stem cell characteristics are lost with aging in humans, affecting skin rejuvenation and structure, and identified specific proteins like Activin A influencing keratinocyte and fibroblast activity.
30 citations
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December 2001 in “Experimental dermatology” This study found that gonadal steroid hormones influence alopecia areata in C3H/HeJ mice, with estradiol promoting progression and dihydrotestosterone conferring resistance to disease onset.
15 citations
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May 2003 in “The Laryngoscope” In this study, researchers observed that spiral ganglion neurites created more branched networks near FGF-1-coupled beads compared to control beads, highlighting FGF-1's role in hair cell innervation development.
9 citations
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February 2014 in “Tissue Engineering and Regenerative Medicine” This study found that conditioned media from human amniotic fluid-derived stem cells may enhance skin regeneration by promoting cell proliferation and migration, and by modulating gene expressions altered by UV irradiation.
6 citations
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October 2013 in “Expert Review of Dermatology” This review explores how psychotropic medications can cause a range of skin reactions, from mild to life-threatening, and emphasizes the importance of monitoring for these adverse effects early in treatment.
3 citations
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August 2024 in “Dermatology and Therapy” This review highlights preclinical and clinical advancements in gene and cell therapies for epidermolysis bullosa and ichthyosis, noting a recently FDA-approved gene therapy for recessive dystrophic EB.
3 citations
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January 2021 in “Skin appendage disorders” This study reports anagen hair loss four weeks after scalp surgeries, likely due to transient ischemia, and emphasizes the importance of informing patients about potential hair loss and recovery within three months.
2 citations
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October 1992 in “PubMed” This study found no significant histologic differences in skin structure based on age, sex, or woodchuck hepatitis virus infection status among woodchucks.
1 citations
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July 2020 in “Iberoamerican Journal of Medicine” This study found that cicatricial alopecia predominantly affects middle-aged Libyan females, with conditions like lichen planopilaris and discoid lupus erythematosus among the most common diagnoses.
July 2019 in “JoLS Journal of Life Sciences” This study found that extracts from the plant Platycodon grandiflorum, particularly the butanol extract, demonstrated potential in preventing hair loss by showing significant antioxidant activity, promoting cell proliferation, and inhibiting inflammation in various cell models.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the occipital scalp had significantly higher epidermal nerve fiber density than the frontoparietal scalp, which may explain increased sensitivity in some patients.
January 2015 in “Journal of the turkish academy of dermatology” This review discusses the evidence and literature on phototherapy for vitiligo but reports no novel clinical findings, highlighting the treatment's reliance on melanocyte reservoirs for repigmentation.
January 2013 in “Journal of Tissue Engineering and Reconstructive Surgery” This study found that inserting isolated hair follicle units into engineered dermis promoted differentiation and maturation of tissue-engineered skin, maintaining hair follicle morphology and generating skin appendages like sebaceous glands.
December 2005 in “TSpace” In this study, diode laser treatment showed approximately 90-95% clearance of lesions in two cases of acne keloidalis nuchae, suggesting it could be a first-line therapy option.
17 citations
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January 1997 in “Cell and Tissue Research” This study found that a serum-free DMEM-F12 medium with 45% oxygen best supports in vitro development and differentiation of human fetal skin, closely mimicking the in vivo state.
3 citations
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June 2021 in “PLOS ONE” This study found that topical application of the BRAF inhibitor vemurafenib improved wound healing and promoted hair follicle regeneration in a diabetic murine model.
385 citations
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November 1990 in “Journal of Cell Science” This study successfully grew and maintained human hair follicles in vitro, noting that TGF-β1 negatively affects growth, while EGF replicates hair-removal effects seen in animals.
76 citations
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January 2007 in “American Journal of Clinical Dermatology” This review discusses the dermatologic features of PCOS as potential early indicators of the syndrome and notes that treatment of these conditions may enhance quality of life and psychological well-being, but it reports no new clinical results.
53 citations
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February 2017 in “Journal of The American Academy of Dermatology” In this study of 20 patients with erosive pustular dermatosis of the scalp, using trichoscopy improved diagnosis, and treatments with high-potency steroids or topical tacrolimus effectively reduced inflammatory signs, suggesting these as first-line treatments.
45 citations
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July 2009 in “Journal of Investigative Dermatology” This study reported significant upregulation and release of S100A4 in psoriatic skin, which may actively contribute to psoriasis pathogenesis.
33 citations
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September 2019 in “Dermatologic Surgery” This study found that intradermal administration of adipose-derived stem cell–conditioned medium significantly increased hair density and dermal thickness, suggesting potential regenerative effects on both hair follicles and the interfollicular scalp in patients with alopecia.
26 citations
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February 1998 in “DNA and Cell Biology” This research identified that the constitutive and inducible expression of the Keratin 6 gene in transgenic mice skin is controlled by multiple regulatory elements spread throughout its 5' flanking region.
21 citations
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September 2013 in “Current medicinal chemistry” This study found that co-drugs synthesized from hydroquinone and tranexamic acid improved skin targeting and deposition, with reduced irritation and enhanced efficacy for treating hyperpigmentation.
20 citations
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August 2017 in “Drug testing and analysis” This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.
19 citations
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December 2012 in “BMC Complementary and Alternative Medicine” This study demonstrates that young coconut juice appears to have estrogen-like properties that can accelerate wound healing in ovariectomized rats.